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NCT04188912 · ClinicalTrials.gov registry record
Close Assessment and Testing for Chronic Graft Versus Host Disease, CATCH Study
A clinical trial, sponsored by Fred Hutchinson Cancer Center.
- Completed
- Registry status
- 267
- Enrollment target
NCT04188912: Completed study, sponsored by Fred Hutchinson Cancer Center.
NCT04188912 is a clinical trial that has completed, run by Fred Hutchinson Cancer Center. The registered enrollment target is 267 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04188912 has completed, sponsored by Fred Hutchinson Cancer Center.
- COMPLETED
- Registry status
- 267 participants
- Enrollment target
Study Summary
This trial observes and collects samples from patients before and after stem cell transplantation to learn more about how and why a complication called chronic graft-versus-host disease (GVHD) develops after stem cell transplantation. Performing close observation and various types of testing may enable doctors to notice symptoms or problems sooner than they would normally have been noticed and predict which patients will develop chronic GVHD.
Primary Outcome
Will compare the pg/ml levels and trajectories of proteins (IL-1b; IL-4; IL-5; IL-6; IL-8; IL-10; IL-13; IL-17a (pg/mL); TNF; G-CSF; IFNgamma; MCP-1; IL-12p40; GM-CSF; IL-2) between patients who do and do not develop chronic graft versus host disease (cGVHD). Blood will be analyzed separately from saliva and conjunctival washings.
Interventions
- PROCEDURE Biospecimen Collection
- OTHER Survey Administration
- PROCEDURE Optical Coherence Tomography
- OTHER Digital Photography
- PROCEDURE Spirometry
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 267 participants |
| Start Date | 2019-09-13 |
| Est. Completion | 2025-09-29 |
What the finished NCT04188912 record still lists
NCT04188912 is an observational study that tracks outcomes without assigning an intervention. The registered 267 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 5 interventions - of which Biospecimen Collection is the first listed.
NCT04188912 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04188912 about?
NCT04188912 is a clinical study titled "Close Assessment and Testing for Chronic Graft Versus Host Disease, CATCH Study". This trial observes and collects samples from patients before and after stem cell transplantation to learn more about how and why a complication called chronic graft-versus-host disease (GVHD) develops after stem cell transplantation. Performing close observation and various types of testing may ena...
What is the current status of trial NCT04188912?
This trial is currently completed. The enrollment target is 267 participants. The study started on 2019-09-13. Estimated completion is 2025-09-29.
What interventions are being tested in trial NCT04188912?
The interventions under investigation include: Biospecimen Collection (PROCEDURE), Survey Administration (OTHER), Optical Coherence Tomography (PROCEDURE), Digital Photography (OTHER), Spirometry (PROCEDURE).
Who is sponsoring clinical trial NCT04188912?
This trial is sponsored by Fred Hutchinson Cancer Center, which has 483 total clinical trials registered on ClinicalTrials.gov.
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