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NCT04186429 · ClinicalTrials.gov registry record
Epigenetic Effects on Traumatic Brain Injury Recovery
A clinical trial, sponsored by University of Pittsburgh.
- Completed
- Registry status
- 401
- Enrollment target
NCT04186429 is a clinical trial that has completed, run by University of Pittsburgh. The registered enrollment target is 401 participants.
The verdict
NCT04186429 has completed, sponsored by University of Pittsburgh.
- COMPLETED
- Registry status
- 401 participants
- Enrollment target
Study Summary
Methylation of the brain-derived neurotrophic factor (BDNF) gene is involved in both the biological encoding of childhood adversity and neuroplasticity following traumatic brain injury (TBI). This research will characterize BDNF methylation during recovery from TBI in children and investigate this novel biomarker as a potential biological mechanism underlying the known association between childhood adversity and poorer neurobehavioral outcomes following TBI in childhood. Findings from this research will contribute to an improved understanding of why some children display good recovery following TBI, whereas many others suffer from chronic neurobehavioral impairments.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 401 participants |
| Start Date | 2017-07-01 |
| Est. Completion | 2024-08-31 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04186429
The ClinicalTrials.gov registry entry for NCT04186429 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 401 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Pittsburgh, which has 1,238 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 0 interventions.
NCT04186429 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT04186429 about?
NCT04186429 is a clinical study titled "Epigenetic Effects on Traumatic Brain Injury Recovery". Methylation of the brain-derived neurotrophic factor (BDNF) gene is involved in both the biological encoding of childhood adversity and neuroplasticity following traumatic brain injury (TBI). This research will characterize BDNF methylation during recovery from TBI in children and investigate this n...
What is the current status of trial NCT04186429?
This trial is currently completed. The enrollment target is 401 participants. The study started on 2017-07-01. Estimated completion is 2024-08-31.
Who is sponsoring clinical trial NCT04186429?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
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