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NCT04182516 · ClinicalTrials.gov registry record · Phase 1
Study of NMS-03305293 in Pts with Selected Advanced/Metastatic Solid Tumors
A Phase 1 study, sponsored by Nerviano Medical Sciences.
- Terminated
- Registry status
- Phase 1
- Development phase
- 52
- Enrollment target
NCT04182516: Clinical Trial Phase 1 study, sponsored by Nerviano Medical Sciences.
NCT04182516 is a Phase 1 study that was terminated before completion, run by Nerviano Medical Sciences. The registered enrollment target is 52 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (13% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04182516, a Phase 1 study, was terminated before completion, sponsored by Nerviano Medical Sciences.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 52 participants
- Enrollment target
Study Summary
Phase I, first-in-human, open-label, multicenter, dose-escalation and dose expansion study with the aim of exploring safety, tolerability and preliminary antitumor activity of NMS-03305293 (a PARP inhibitor) as single agent in adult patients with selected advanced/metastatic, relapsed/refractory solid tumors who have exhausted standard treatment options or for whom standard therapy is considered unsuitable.
Interventions
- DRUG NMS-03305293
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 52 participants |
| Start Date | 2019-11-25 |
| Est. Completion | 2024-05-16 |
| Phase | Phase 1 |
Why NCT04182516 stopped before completion
NCT04182516 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 52 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (13% lower).
The record links to 0 conditions, and to 1 intervention - of which NMS-03305293 is the first listed.
NCT04182516 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04182516 about?
NCT04182516 is a clinical study titled "Study of NMS-03305293 in Pts with Selected Advanced/Metastatic Solid Tumors". Phase I, first-in-human, open-label, multicenter, dose-escalation and dose expansion study with the aim of exploring safety, tolerability and preliminary antitumor activity of NMS-03305293 (a PARP inhibitor) as single agent in adult patients with selected advanced/metastatic, relapsed/refractory sol...
What is the current status of trial NCT04182516?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 52 participants. The study started on 2019-11-25. Estimated completion is 2024-05-16.
What interventions are being tested in trial NCT04182516?
The interventions under investigation include: NMS-03305293 (DRUG).
Who is sponsoring clinical trial NCT04182516?
This trial is sponsored by Nerviano Medical Sciences, which has 11 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04182516's enrollment target sits among peer trials
52 956th of 2000 higher than 1,032 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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