Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04181463 · ClinicalTrials.gov registry record · Phase 2
Nasal Inhalation of Isopropyl Alcohol for the Treatment of Nausea in Patients With Cancer
A Phase 2 study, sponsored by M.D. Anderson Cancer Center.
- Not yet
- Registry status
- Phase 2
- Development phase
- 112
- Enrollment target
NCT04181463: Clinical Trial Phase 2 study, sponsored by M.D. Anderson Cancer Center.
NCT04181463 is a Phase 2 study that has not yet begun recruiting, run by M.D. Anderson Cancer Center. The registered enrollment target is 112 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (16% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04181463, a Phase 2 study, has not yet begun recruiting, sponsored by M.D. Anderson Cancer Center.
- NOT YET RECRUITING
- Registry status
- Phase 2
- Development phase
- 112 participants
- Enrollment target
Study Summary
The goal of this research study is to understand the effect of inhalation approaches in reducing nausea in cancer patients.
Primary Outcome
The mean change in nausea level will be compared between the two arms by two sample t-test. In case there's any violation in the underlying assumptions (e.g. normality, equality of variance, etc.) proper transformation (e.g. logarithm, square root, etc.) or non-parametric methods (Wilcoxon rank sum test) will be applied.
Interventions
- OTHER Placebo
- OTHER Questionnaire Administration
- DRUG Isopropyl Alcohol
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 112 participants |
| Start Date | 2026-11-05 |
| Est. Completion | 2028-12-30 |
| Phase | Phase 2 |
What is known before NCT04181463 opens enrollment
NCT04181463 is an interventional study that assigns participants to a tested intervention. The registered 112 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (16% lower).
The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.
NCT04181463 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04181463 about?
NCT04181463 is a clinical study titled "Nasal Inhalation of Isopropyl Alcohol for the Treatment of Nausea in Patients With Cancer". The goal of this research study is to understand the effect of inhalation approaches in reducing nausea in cancer patients.
What is the current status of trial NCT04181463?
This trial is currently not yet recruiting. It is a Phase 2 study. The enrollment target is 112 participants. The study started on 2026-11-05. Estimated completion is 2028-12-30.
What interventions are being tested in trial NCT04181463?
The interventions under investigation include: Placebo (OTHER), Questionnaire Administration (OTHER), Isopropyl Alcohol (DRUG).
Who is sponsoring clinical trial NCT04181463?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04181463's enrollment target sits among peer trials
112 631st of 2000 higher than 1,369 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT04511013 · 112 participants · Phase 2
A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases
- NCT04551560 · 112 participants · NA
Stress and Congestive Heart Failure
- NCT04872166 · 112 participants · Phase 1
A Study of BTX-A51 in People With Advanced Solid Tumor and Breast Cancer
- NCT05024773 · 112 participants · Phase 3
Study of ONCOFID-P-B (PACLITAXEL-HYALURONIC ACID)
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI