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NCT04177498 · ClinicalTrials.gov registry record · Early Phase 1

Rigosertib in Patients With Recessive Dystrophic Epidermolysis Bullosa Associated SCC

A Early Phase 1 study, sponsored by Thomas Jefferson University.

Completed
Registry status
Early Phase 1
Development phase
3
Enrollment target

NCT04177498 is a Early Phase 1 study that has completed, run by Thomas Jefferson University. The registered enrollment target is 3 participants.

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The verdict

NCT04177498, a Early Phase 1 study, has completed, sponsored by Thomas Jefferson University.

COMPLETED
Registry status
Early Phase 1
Development phase
3 participants
Enrollment target

Study Summary

This pilot trial studies how rigsertib sodium works in treating patients with Recessive Dystrophic Epidermolysis bullosa (RDEB) with locally advanced Squamous Cell Carcinoma (SCC). Rigosertib may selectively target Epidermolysis bullosa (EB) cancer cells while leaving normal EB cells unaffected.

Interventions

  • OTHER Quality-of-Life Assessment
  • DRUG Rigosertib Sodium

Trial Details

FieldValue
Enrollment Target 3 participants
Start Date 2021-08-24
Est. Completion 2025-05-05
Phase Early Phase 1

Sponsor

Thomas Jefferson University

292 total trials

What the Registry Record Tells You About NCT04177498

The ClinicalTrials.gov registry entry for NCT04177498 describes a study currently listed as completed, categorized as Early Phase 1. The registered enrollment target is 3 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Thomas Jefferson University, which has 292 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Quality-of-Life Assessment is the first listed.

NCT04177498 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04177498 about?

NCT04177498 is a clinical study titled "Rigosertib in Patients With Recessive Dystrophic Epidermolysis Bullosa Associated SCC". This pilot trial studies how rigsertib sodium works in treating patients with Recessive Dystrophic Epidermolysis bullosa (RDEB) with locally advanced Squamous Cell Carcinoma (SCC). Rigosertib may selectively target Epidermolysis bullosa (EB) cancer cells while leaving normal EB cells unaffected.

What is the current status of trial NCT04177498?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 3 participants. The study started on 2021-08-24. Estimated completion is 2025-05-05.

What interventions are being tested in trial NCT04177498?

The interventions under investigation include: Quality-of-Life Assessment (OTHER), Rigosertib Sodium (DRUG).

Who is sponsoring clinical trial NCT04177498?

This trial is sponsored by Thomas Jefferson University, which has 292 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.