Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT04175626 · ClinicalTrials.gov registry record

Safety and Effectiveness of the Orsiro Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions

A clinical trial, sponsored by Biotronik.

Completed
Registry status
556
Enrollment target

NCT04175626: Completed study, sponsored by Biotronik.

NCT04175626 is a clinical trial that has completed, run by Biotronik. The registered enrollment target is 556 participants. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT04175626 has completed, sponsored by Biotronik.

COMPLETED
Registry status
556 participants
Enrollment target

Study Summary

The objective of this post-approval study is to confirm that the clinical performance of the Orsiro stent in a real-world setting is similar to the clinical performance observed for Orsiro in the BIOFLOW-V Investigational Device Exemption pivotal trial, as a condition of the US Food and Drug Administration (FDA) approval (P170030).

Primary Outcome

TLF is defined as all cardiac death, target vessel Q-wave or non-Q-wave myocardial infarction (MI), or clinically driven target lesion revascularization (TLR).

Interventions

  • DEVICE Orsiro DES

Trial Details

FieldValue
Enrollment Target 556 participants
Start Date 2020-01-24
Est. Completion 2026-01-08
Biotronik

30 total trials

What the finished NCT04175626 record still lists

NCT04175626 is an observational study that tracks outcomes without assigning an intervention. The registered 556 participants enrollment target is mid-sized for trials with a published cap.

The record links to 0 conditions, and to 1 intervention - of which Orsiro DES is the first listed.

NCT04175626 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04175626 about?

NCT04175626 is a clinical study titled "Safety and Effectiveness of the Orsiro Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions". The objective of this post-approval study is to confirm that the clinical performance of the Orsiro stent in a real-world setting is similar to the clinical performance observed for Orsiro in the BIOFLOW-V Investigational Device Exemption pivotal trial, as a condition of the US Food and Drug Adminis...

What is the current status of trial NCT04175626?

This trial is currently completed. The enrollment target is 556 participants. The study started on 2020-01-24. Estimated completion is 2026-01-08.

What interventions are being tested in trial NCT04175626?

The interventions under investigation include: Orsiro DES (DEVICE).

Who is sponsoring clinical trial NCT04175626?

This trial is sponsored by Biotronik, which has 30 total clinical trials registered on ClinicalTrials.gov.

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT06074588 · 556 participants · Phase 3

    Sacituzumab Tirumotecan (MK-2870) Versus Chemotherapy in Previously Treated Advanced or Metastatic Nonsquamous Non-small Cell Lung Cancer (NSCLC) With EGFR Mutations or Other Genomic Alterations (MK-2870-004)

  • NCT06693622 · 556 participants

    Patient Preferences for Barrett's Esophagus and Esophageal Cancer Screening Tests

  • NCT05708885 · 557 participants · NA

    Striated Esophageal Motor Function Modulation in Health and Disease

  • NCT06799000 · 555 participants · Phase 3

    A Phase 3 Study to Assess Efficacy Safety and Tolerability of Remibrutinib in Adult and Adolescent Patients With Moderate to Severe Hidradenitis Suppurativa (RECHARGE 1)

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT04175626, the US trial registry maintained by the National Library of Medicine. NCT04175626 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.