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NCT04169776 · ClinicalTrials.gov registry record · NA
Effect of Daily Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) on Proteinuria in Pediatric Patients With Idiopathic Nephrotic Syndrome
A NA study, sponsored by Northwell Health.
- Completed
- Registry status
- NA
- Development phase
- 7
- Enrollment target
NCT04169776: Completed NA study, sponsored by Northwell Health.
NCT04169776 is a NA study that has completed, run by Northwell Health. The registered enrollment target is 7 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04169776, a NA study, has completed, sponsored by Northwell Health.
- COMPLETED
- Registry status
- NA
- Development phase
- 7 participants
- Enrollment target
Study Summary
This study evaluates the impact of transcutaneous auricular Vagus Nerve stimulation (taVNS) therapy on the incidence of nephrotic syndrome relapses in children with idiopathic nephrotic syndrome. Participants will perform taVNS 5 minutes a day for 6 months total, monitoring for signs of nephrotic syndrome relapse with both labwork and clinical symptoms.
Primary Outcome
The endpoint of heart rate monitoring as a measure of safety of taVNS in this population was selected as this is the most concerning adverse effect of taVNS therapy. If there is no heart rate-related events during this study, it would further justify safe use of taVNS in the pediatric population. Tolerability is an important measure in this study but is mostly a subjective measure. Therefore, patients who withdraw due to intolerability or report side effects which are deemed intolerable will ai
Interventions
- DEVICE Transcutaneous Auricular Vagus Nerve (taVNS) stimulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7 participants |
| Start Date | 2019-12-01 |
| Est. Completion | 2021-12-01 |
| Phase | NA |
What the finished NCT04169776 record still lists
NCT04169776 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 7 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 1 intervention - of which Transcutaneous Auricular Vagus Nerve (taVNS) stimulation is the first listed.
NCT04169776 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04169776 about?
NCT04169776 is a clinical study titled "Effect of Daily Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) on Proteinuria in Pediatric Patients With Idiopathic Nephrotic Syndrome". This study evaluates the impact of transcutaneous auricular Vagus Nerve stimulation (taVNS) therapy on the incidence of nephrotic syndrome relapses in children with idiopathic nephrotic syndrome. Participants will perform taVNS 5 minutes a day for 6 months total, monitoring for signs of nephrotic sy...
What is the current status of trial NCT04169776?
This trial is currently completed. It is a NA study. The enrollment target is 7 participants. The study started on 2019-12-01. Estimated completion is 2021-12-01.
What interventions are being tested in trial NCT04169776?
The interventions under investigation include: Transcutaneous Auricular Vagus Nerve (taVNS) stimulation (DEVICE).
Who is sponsoring clinical trial NCT04169776?
This trial is sponsored by Northwell Health, which has 370 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04169776's enrollment target sits among peer trials
7 1982nd of 2000 higher than 18 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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