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NCT04163952 · ClinicalTrials.gov registry record · Phase 1

Talimogene Laherparepvec and Panitumumab for the Treatment of Locally Advanced or Metastatic Squamous Cell Carcinoma of the Skin

A Phase 1 study, sponsored by Rutgers, The State University of New Jersey.

Terminated
Registry status
Phase 1
Development phase
5
Enrollment target

NCT04163952 is a Phase 1 study that was terminated before completion, run by Rutgers, The State University of New Jersey. The registered enrollment target is 5 participants.

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The verdict

NCT04163952, a Phase 1 study, was terminated before completion, sponsored by Rutgers, The State University of New Jersey.

TERMINATED
Registry status
Phase 1
Development phase
5 participants
Enrollment target

Study Summary

This phase I trial studies the side effects and how well talimogene laherparepvec and panitumumab work in treating patients with squamous cell carcinoma of the skin that has spread to nearby tissues or lymph nodes (locally advanced) or other places in the body (metastatic). Talimogene laherparepvec is a type of vaccine made from a gene-modified virus that may help the body build an effective immune response to kill tumor cells. Immunotherapy with monoclonal antibodies, such as panitumumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving talimogene laherparepvec and panitumumab may work better in treating patients with squamous cell carcinoma of the skin compared to panitumumab alone.

Interventions

  • BIOLOGICAL Panitumumab
  • BIOLOGICAL Talimogene Laherparepvec

Trial Details

FieldValue
Enrollment Target 5 participants
Start Date 2020-01-31
Est. Completion 2025-03-28
Phase Phase 1

What the Registry Record Tells You About NCT04163952

The ClinicalTrials.gov registry entry for NCT04163952 describes a study currently listed as terminated, categorized as Phase 1. The registered enrollment target is 5 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Rutgers, The State University of New Jersey, which has 413 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Panitumumab is the first listed.

NCT04163952 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04163952 about?

NCT04163952 is a clinical study titled "Talimogene Laherparepvec and Panitumumab for the Treatment of Locally Advanced or Metastatic Squamous Cell Carcinoma of the Skin". This phase I trial studies the side effects and how well talimogene laherparepvec and panitumumab work in treating patients with squamous cell carcinoma of the skin that has spread to nearby tissues or lymph nodes (locally advanced) or other places in the body (metastatic). Talimogene laherparepvec ...

What is the current status of trial NCT04163952?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 5 participants. The study started on 2020-01-31. Estimated completion is 2025-03-28.

What interventions are being tested in trial NCT04163952?

The interventions under investigation include: Panitumumab (BIOLOGICAL), Talimogene Laherparepvec (BIOLOGICAL).

Who is sponsoring clinical trial NCT04163952?

This trial is sponsored by Rutgers, The State University of New Jersey, which has 413 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.