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NCT04161482 · ClinicalTrials.gov registry record · Phase 1

An Open Label Study to Evaluate the Impact of Duration of Subcutaneous Infusion of a Novel, pH Neutral Formulation of Furosemide (Furoscix®) on Safety and Local Skin Tolerability

A Phase 1 study, sponsored by scPharmaceuticals.

Completed
Registry status
Phase 1
Development phase
39
Enrollment target

NCT04161482: Completed Phase 1 study, sponsored by scPharmaceuticals.

NCT04161482 is a Phase 1 study that has completed, run by scPharmaceuticals. The registered enrollment target is 39 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (35% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT04161482, a Phase 1 study, has completed, sponsored by scPharmaceuticals.

COMPLETED
Registry status
Phase 1
Development phase
39 participants
Enrollment target

Study Summary

This is a Phase 1 study to evaluate the safety and tolerability of shortened subcutaneous infusions of Furoscix.

Primary Outcome

Assessment of pain will be conducted upon placement of the subcutaneous (SC) needle, upon activation of SC infusion and periodically during the infusion and post-infusion completion for up to 8 hours after the start of the infusion using a standardized 11 point pain scale. Score will range from 0 to 10, where zero is equivalent to no pain and 10 is equivalent to the worst possible pain.

Interventions

  • DRUG Furosemide 80 mg (8 mg/mL)

Trial Details

FieldValue
Enrollment Target 39 participants
Start Date 2019-12-02
Est. Completion 2020-06-26
Phase Phase 1
scPharmaceuticals

5 total trials

What the finished NCT04161482 record still lists

NCT04161482 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 39 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (35% lower).

The record links to 0 conditions, and to 1 intervention - of which Furosemide 80 mg (8 mg/mL) is the first listed.

NCT04161482 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04161482 about?

NCT04161482 is a clinical study titled "An Open Label Study to Evaluate the Impact of Duration of Subcutaneous Infusion of a Novel, pH Neutral Formulation of Furosemide (Furoscix®) on Safety and Local Skin Tolerability". This is a Phase 1 study to evaluate the safety and tolerability of shortened subcutaneous infusions of Furoscix.

What is the current status of trial NCT04161482?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 39 participants. The study started on 2019-12-02. Estimated completion is 2020-06-26.

What interventions are being tested in trial NCT04161482?

The interventions under investigation include: Furosemide 80 mg (8 mg/mL) (DRUG).

Who is sponsoring clinical trial NCT04161482?

This trial is sponsored by scPharmaceuticals, which has 5 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04161482's enrollment target sits among peer trials

39 1191st of 2000 higher than 804 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04161482, the US trial registry maintained by the National Library of Medicine. NCT04161482 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.