Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04159207 · ClinicalTrials.gov registry record
A Longitudinal Study of Inflammatory Pathways in Depression
A clinical trial, sponsored by Van Andel Research Institute.
- Completed
- Registry status
- 130
- Enrollment target
NCT04159207: Completed study, sponsored by Van Andel Research Institute.
NCT04159207 is a clinical trial that has completed, run by Van Andel Research Institute. The registered enrollment target is 130 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04159207 has completed, sponsored by Van Andel Research Institute.
- COMPLETED
- Registry status
- 130 participants
- Enrollment target
Study Summary
Suicide accounts for at least 1 million deaths globally each year. This is likely a significant underestimate, because suicide is under-reported in many countries. In the US, over 42,000 people die from suicide annually. Despite increased focus on identification and treatment, the rate of suicide has increased steadily over the past 15 years. Our project aims both to improve our understanding of factors that increase the risk for suicide by comparing blood biomarkers associated with inflammation in patients with depression without suicidal behavior and patients with depression and suicidal behavior. The 160 individuals in this study will be followed with psychiatric assessments and blood samples at repeated time points over one year.
Primary Outcome
The presence of suicidal behavior over one year will be classified as yes/no as the primary outcome measure. The Identification of participants with suicidal behavior at each study time point will be achieved by assessment using the Columbia Suicide Severity Rating Scale (C-SSRS) regarding attempt, interrupted or aborted attempt, or preparatory acts over the past 7 days.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 130 participants |
| Start Date | 2019-10-01 |
| Est. Completion | 2023-08-30 |
What the finished NCT04159207 record still lists
NCT04159207 is an observational study that tracks outcomes without assigning an intervention. The registered 130 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT04159207 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04159207 about?
NCT04159207 is a clinical study titled "A Longitudinal Study of Inflammatory Pathways in Depression". Suicide accounts for at least 1 million deaths globally each year. This is likely a significant underestimate, because suicide is under-reported in many countries. In the US, over 42,000 people die from suicide annually. Despite increased focus on identification and treatment, the rate of suicide ha...
What is the current status of trial NCT04159207?
This trial is currently completed. The enrollment target is 130 participants. The study started on 2019-10-01. Estimated completion is 2023-08-30.
Who is sponsoring clinical trial NCT04159207?
This trial is sponsored by Van Andel Research Institute, which has 3 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01492036 · 130 participants
Long-Term Follow-Up of Recipient of Gene Transfer Research
- NCT01631617 · 130 participants · Phase 2
Effects of Treatments on Atopic Dermatitis
- NCT02368041 · 130 participants
Utility of Thenar Near Infrared Spectroscopy (NIRS) in Pediatric Patients With Heart Failure
- NCT02604277 · 130 participants · NA
Suicidal Behavior in Patients Diagnosed With Bipolar Disorder
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI