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NCT04157036 · ClinicalTrials.gov registry record · Phase 3
Evaluation of Methylprednisolone or Ibuprofen on Efficacy of Nerve Blocks With Symptomatic Irreversible Pulpitis
A Phase 3 study, sponsored by Walter Reed National Military Medical Center.
- Terminated
- Registry status
- Phase 3
- Development phase
- 3
- Enrollment target
NCT04157036: Clinical Trial Phase 3 study, sponsored by Walter Reed National Military Medical Center.
NCT04157036 is a Phase 3 study that was terminated before completion, run by Walter Reed National Military Medical Center. The registered enrollment target is 3 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04157036, a Phase 3 study, was terminated before completion, sponsored by Walter Reed National Military Medical Center.
- TERMINATED
- Registry status
- Phase 3
- Development phase
- 3 participants
- Enrollment target
Study Summary
This prospective, randomized, double-blind study will compare the effect of oral premedication of ibuprofen and methylprednisolone on the anesthetic efficacy of an Inferior Alveolar Nerve Block (IANB) in adult patients with symptomatic irreversible pulpitis.
Primary Outcome
To compare the effect of two oral pre-medications, ibuprofen and methylprednisolone, on the anesthetic efficacy of the inferior alveolar nerve block (IANB) using a VAS scale in patients with symptomatic irreversible pulpitis. The scale is 100mm long. If the subject experiences pain during the procedure, he/she will mark the scale. If it is marked at 50mm or lower, the nerve block is considered a success (no or mild pain), if it is marked above 50mm, the nerve block failed and supplemental anesth
Interventions
- DRUG Ibuprofen
- DRUG Methylprednisolone
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3 participants |
| Start Date | 2020-02-01 |
| Est. Completion | 2021-10-06 |
| Phase | Phase 3 |
Why NCT04157036 stopped before completion
NCT04157036 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 2 interventions - of which Ibuprofen is the first listed.
NCT04157036 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04157036 about?
NCT04157036 is a clinical study titled "Evaluation of Methylprednisolone or Ibuprofen on Efficacy of Nerve Blocks With Symptomatic Irreversible Pulpitis". This prospective, randomized, double-blind study will compare the effect of oral premedication of ibuprofen and methylprednisolone on the anesthetic efficacy of an Inferior Alveolar Nerve Block (IANB) in adult patients with symptomatic irreversible pulpitis.
What is the current status of trial NCT04157036?
This trial is currently terminated. It is a Phase 3 study. The enrollment target is 3 participants. The study started on 2020-02-01. Estimated completion is 2021-10-06.
What interventions are being tested in trial NCT04157036?
The interventions under investigation include: Ibuprofen (DRUG), Methylprednisolone (DRUG).
Who is sponsoring clinical trial NCT04157036?
This trial is sponsored by Walter Reed National Military Medical Center, which has 48 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04157036's enrollment target sits among peer trials
3 1999th of 2000 higher than 1 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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