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NCT04150718 · ClinicalTrials.gov registry record · NA
Role of Slow-wave Activity and Plasticity in MDD
A NA study, sponsored by University of Pennsylvania.
- Completed
- Registry status
- NA
- Development phase
- 77
- Enrollment target
NCT04150718: Completed NA study, sponsored by University of Pennsylvania.
NCT04150718 is a NA study that has completed, run by University of Pennsylvania. The registered enrollment target is 77 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04150718, a NA study, has completed, sponsored by University of Pennsylvania.
- COMPLETED
- Registry status
- NA
- Development phase
- 77 participants
- Enrollment target
Study Summary
The hypothesis underlying this proposal is that deficits of synaptic plasticity underlie the slow-wave activity (SWA) abnormalities observed n major depressive disorder (MDD), and that manipulating SWA may serve to circumvent these deficits by facilitating an increase in synaptic strength via the inhibition of synaptic down-scaling, thereby improving plasticity and mood.
Primary Outcome
Transcranial magnetic stimulation evoked potentials (MEP) - Measure of the amplitude of muscle movement from hand following TMS
Interventions
- BEHAVIORAL slow-wave disruption
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 77 participants |
| Start Date | 2020-03-04 |
| Est. Completion | 2024-07-01 |
| Phase | NA |
What the finished NCT04150718 record still lists
NCT04150718 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 77 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 1 intervention - of which slow-wave disruption is the first listed.
NCT04150718 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04150718 about?
NCT04150718 is a clinical study titled "Role of Slow-wave Activity and Plasticity in MDD". The hypothesis underlying this proposal is that deficits of synaptic plasticity underlie the slow-wave activity (SWA) abnormalities observed n major depressive disorder (MDD), and that manipulating SWA may serve to circumvent these deficits by facilitating an increase in synaptic strength via the in...
What is the current status of trial NCT04150718?
This trial is currently completed. It is a NA study. The enrollment target is 77 participants. The study started on 2020-03-04. Estimated completion is 2024-07-01.
What interventions are being tested in trial NCT04150718?
The interventions under investigation include: slow-wave disruption (BEHAVIORAL).
Who is sponsoring clinical trial NCT04150718?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04150718's enrollment target sits among peer trials
77 1062nd of 2000 higher than 939 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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