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NCT04150029 · ClinicalTrials.gov registry record · Phase 2

A Study of MBG453 in Combination With Azacitidine and Venetoclax in AML Patients Unfit for Chemotherapy

A Phase 2 study, sponsored by Novartis Pharmaceuticals.

Terminated
Registry status
Phase 2
Development phase
90
Enrollment target

NCT04150029 is a Phase 2 study that was terminated before completion, run by Novartis Pharmaceuticals. The registered enrollment target is 90 participants.

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The verdict

NCT04150029, a Phase 2 study, was terminated before completion, sponsored by Novartis Pharmaceuticals.

TERMINATED
Registry status
Phase 2
Development phase
90 participants
Enrollment target

Study Summary

This trial seeked to extend the preliminary findings of efficacy by evaluating MBG453 in combination with hypomethylating agents (HMA) and also Bcl-2 inhibitor venetoclax.

Interventions

  • DRUG Venetoclax
  • DRUG Azacitidine
  • DRUG MBG453

Trial Details

FieldValue
Enrollment Target 90 participants
Start Date 2020-09-01
Est. Completion 2024-10-25
Phase Phase 2

Sponsor

Novartis Pharmaceuticals

1,375 total trials

What the Registry Record Tells You About NCT04150029

The ClinicalTrials.gov registry entry for NCT04150029 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 90 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Novartis Pharmaceuticals, which has 1,375 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Venetoclax is the first listed.

NCT04150029 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04150029 about?

NCT04150029 is a clinical study titled "A Study of MBG453 in Combination With Azacitidine and Venetoclax in AML Patients Unfit for Chemotherapy". This trial seeked to extend the preliminary findings of efficacy by evaluating MBG453 in combination with hypomethylating agents (HMA) and also Bcl-2 inhibitor venetoclax.

What is the current status of trial NCT04150029?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 90 participants. The study started on 2020-09-01. Estimated completion is 2024-10-25.

What interventions are being tested in trial NCT04150029?

The interventions under investigation include: Venetoclax (DRUG), Azacitidine (DRUG), MBG453 (DRUG).

Who is sponsoring clinical trial NCT04150029?

This trial is sponsored by Novartis Pharmaceuticals, which has 1,375 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.