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NCT04147858 · ClinicalTrials.gov registry record · Phase 2
Efficacy and Safety of NYX-2925 in Subjects With Fibromyalgia
A Phase 2 study, sponsored by Aptinyx.
- Completed
- Registry status
- Phase 2
- Development phase
- 310
- Enrollment target
NCT04147858: Completed Phase 2 study, sponsored by Aptinyx.
NCT04147858 is a Phase 2 study that has completed, run by Aptinyx. The registered enrollment target is 310 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (133% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04147858, a Phase 2 study, has completed, sponsored by Aptinyx.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 310 participants
- Enrollment target
Study Summary
To evaluate the efficacy of NYX-2925 versus placebo for the treatment of fibromyalgia.
Primary Outcome
Change from baseline to Week 12 in the weekly mean of the daily Numerical Rating Scale (NRS) score assessing average pain intensity in the past 24 hours, scores range from 0-10, with higher scores indicating worse pain (0 being no pain and 10 being the worst possible pain)
Interventions
- DRUG Placebo
- DRUG NYX-2925
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 310 participants |
| Start Date | 2019-11-12 |
| Est. Completion | 2022-06-16 |
| Phase | Phase 2 |
What the finished NCT04147858 record still lists
NCT04147858 is an interventional study that assigns participants to a tested intervention. The registered 310 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (133% higher).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT04147858 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04147858 about?
NCT04147858 is a clinical study titled "Efficacy and Safety of NYX-2925 in Subjects With Fibromyalgia". To evaluate the efficacy of NYX-2925 versus placebo for the treatment of fibromyalgia.
What is the current status of trial NCT04147858?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 310 participants. The study started on 2019-11-12. Estimated completion is 2022-06-16.
What interventions are being tested in trial NCT04147858?
The interventions under investigation include: Placebo (DRUG), NYX-2925 (DRUG).
Who is sponsoring clinical trial NCT04147858?
This trial is sponsored by Aptinyx, which has 8 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04147858's enrollment target sits among peer trials
310 162nd of 2000 higher than 1,838 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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