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NCT04146051 · ClinicalTrials.gov registry record · Phase 2
Descartes-08 CAR-T Cells in Generalized Myasthenia Gravis (MG)
A Phase 2 study of Myasthenia Gravis, Generalized, sponsored by Cartesian Therapeutics.
- Active
- Registry status
- Phase 2
- Development phase
- 30
- Enrollment target
- 15
- Study locations
NCT04146051 is a Phase 2 study of Myasthenia Gravis, Generalized that is active but no longer recruiting, run by Cartesian Therapeutics. The registered enrollment target is 30 participants, below the 1,328-participant average among 3 other Myasthenia Gravis, Generalized trials with a reported enrollment target (98% lower). The trial reports 15 study locations across 11 states.
The verdict
NCT04146051, a Phase 2 study of Myasthenia Gravis, Generalized, is active but no longer recruiting, sponsored by Cartesian Therapeutics.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 30 participants
- Enrollment target
- 15
- Study locations
Study Summary
This is a Phase IIb study to evaluate the safety and preliminary efficacy of Descartes-08 CAR T-cells in patients with Generalized Myasthenia Gravis
Conditions Studied
Interventions
- DRUG Descartes-08
Study Locations (15)
Florida
- SFM Clinical Research, LLC - Boca Raton
- Neurology Associates, P.A. - Orlando
- University of South Florida - Tampa
California
- Profound Research - Carlsbad
- University of California Irvine - Irvine
Pennsylvania
- University of Pennsylvania - Philadelphia
- Allegheny Health Network - Pittsburgh
Colorado
- University of Colorado Anschutz Medical Campus - Aurora
Georgia
- University of Augusta - Augusta
Kansas
- University of Kansas Medical Center Research Institute - Kansas City
New York
- Dent Neurologic Institute - Amherst
North Carolina
- University of North Carolina - Chapel Hill
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2019-12-04 |
| Est. Completion | 2026-03-31 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04146051
The ClinicalTrials.gov registry entry for NCT04146051 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,328-participant average among 3 other Myasthenia Gravis, Generalized trials with a reported enrollment target (98% lower). The listed sponsor is Cartesian Therapeutics, which has 12 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Myasthenia Gravis, Generalized appearing as the primary indexed condition, and to 1 intervention - of which Descartes-08 is the first listed.
NCT04146051 reports 15 study locations spanning 11 distinct geographic areas - top geographies include Florida, California, Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT04146051 about?
NCT04146051 is a clinical study titled "Descartes-08 CAR-T Cells in Generalized Myasthenia Gravis (MG)". This is a Phase IIb study to evaluate the safety and preliminary efficacy of Descartes-08 CAR T-cells in patients with Generalized Myasthenia Gravis
What is the current status of trial NCT04146051?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 30 participants. The study started on 2019-12-04. Estimated completion is 2026-03-31.
What conditions does trial NCT04146051 study?
This clinical trial studies the following conditions: Myasthenia Gravis, Generalized.
What interventions are being tested in trial NCT04146051?
The interventions under investigation include: Descartes-08 (DRUG).
Who is sponsoring clinical trial NCT04146051?
This trial is sponsored by Cartesian Therapeutics, which has 12 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04146051 being conducted?
This trial has 15 study locations across California, Colorado, Florida, Georgia, Kansas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.