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NCT04145297 · ClinicalTrials.gov registry record · Phase 1
Ulixertinib (BVD-523) and Hydroxychloroquine in Patients W Advanced MAPK-Mutated Gastrointestinal Adenocarcinomas
A Phase 1 study, sponsored by University of Utah.
- Completed
- Registry status
- Phase 1
- Development phase
- 16
- Enrollment target
NCT04145297: Completed Phase 1 study, sponsored by University of Utah.
NCT04145297 is a Phase 1 study that has completed, run by University of Utah. The registered enrollment target is 16 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04145297, a Phase 1 study, has completed, sponsored by University of Utah.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 16 participants
- Enrollment target
Study Summary
Open-label dose escalation of Ulixertinib combined with fixed dose of hydroxychloroquine.
Primary Outcome
The incidence of DLTs during the defined DLT period
Interventions
- DRUG Ulixertinib
- DRUG Hydroxychloroquine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2020-03-17 |
| Est. Completion | 2022-08-18 |
| Phase | Phase 1 |
What the finished NCT04145297 record still lists
NCT04145297 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower).
The record links to 0 conditions, and to 2 interventions - of which Ulixertinib is the first listed.
NCT04145297 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04145297 about?
NCT04145297 is a clinical study titled "Ulixertinib (BVD-523) and Hydroxychloroquine in Patients W Advanced MAPK-Mutated Gastrointestinal Adenocarcinomas". Open-label dose escalation of Ulixertinib combined with fixed dose of hydroxychloroquine.
What is the current status of trial NCT04145297?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2020-03-17. Estimated completion is 2022-08-18.
What interventions are being tested in trial NCT04145297?
The interventions under investigation include: Ulixertinib (DRUG), Hydroxychloroquine (DRUG).
Who is sponsoring clinical trial NCT04145297?
This trial is sponsored by University of Utah, which has 818 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04145297's enrollment target sits among peer trials
16 1786th of 2000 higher than 203 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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