Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04142086 · ClinicalTrials.gov registry record · Phase 1
Dose-ranging Study of an Investigational Yellow Fever Candidate Vaccine in Adults
A Phase 1 study, sponsored by Sanofi Pasteur, a Sanofi Company.
- Completed
- Registry status
- Phase 1
- Development phase
- 73
- Enrollment target
NCT04142086 is a Phase 1 study that has completed, run by Sanofi Pasteur, a Sanofi Company. The registered enrollment target is 73 participants.
The verdict
NCT04142086, a Phase 1 study, has completed, sponsored by Sanofi Pasteur, a Sanofi Company.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 73 participants
- Enrollment target
Study Summary
The primary objectives of the study are: * To describe the safety profile of each of the 3 dosages of vYF and of YF-VAX® within the 28 days post-vaccination and up to the 6 months (Day 180) post-vaccination visit * To describe the antibody responses elicited by each of the 3 dosages of vYF and by YF-VAX on Day 0 pre-vaccination and then on Day 10, Day 14, Day 28 and 6 months (Day 180) post-vaccination overall and by baseline flavivirus serostatus * To quantify the detectable yellow fever (YF) vaccinal viremia in each vaccine groups (vYF and YF-VAX) in a subset of subjects on Day 0 visit, Day 1 visit, Day 3 visit, Day 5 visit, Day 7 visit, Day 10 visit, and Day 14 visit.
Interventions
- BIOLOGICAL Yellow fever vaccine
- BIOLOGICAL Yellow fever vaccine (produced on serum-free Vero cells), Dosage 1 vYF vaccine
- BIOLOGICAL Yellow fever vaccine (produced on serum-free Vero cells), Dosage 2 vYF vaccine
- BIOLOGICAL Yellow fever vaccine (produced on serum-free Vero cells), Dosage 3 vYF vaccine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 73 participants |
| Start Date | 2020-01-15 |
| Est. Completion | 2021-06-24 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04142086
The ClinicalTrials.gov registry entry for NCT04142086 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 73 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Sanofi Pasteur, a Sanofi Company, which has 153 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 4 interventions - of which Yellow fever vaccine is the first listed.
NCT04142086 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT04142086 about?
NCT04142086 is a clinical study titled "Dose-ranging Study of an Investigational Yellow Fever Candidate Vaccine in Adults". The primary objectives of the study are: * To describe the safety profile of each of the 3 dosages of vYF and of YF-VAX® within the 28 days post-vaccination and up to the 6 months (Day 180) post-vaccination visit * To describe the antibody responses elicited by each of the 3 dosages of vYF and by Y...
What is the current status of trial NCT04142086?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 73 participants. The study started on 2020-01-15. Estimated completion is 2021-06-24.
What interventions are being tested in trial NCT04142086?
The interventions under investigation include: Yellow fever vaccine (BIOLOGICAL), Yellow fever vaccine (produced on serum-free Vero cells), Dosage 1 vYF vaccine (BIOLOGICAL), Yellow fever vaccine (produced on serum-free Vero cells), Dosage 2 vYF vaccine (BIOLOGICAL), Yellow fever vaccine (produced on serum-free Vero cells), Dosage 3 vYF vaccine (BIOLOGICAL).
Who is sponsoring clinical trial NCT04142086?
This trial is sponsored by Sanofi Pasteur, a Sanofi Company, which has 153 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.