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NCT04139226 · ClinicalTrials.gov registry record · Phase 1

A Study to Evaluate the Safety, Tolerability Pharmacokinetics, and Pharmacodynamics of a New Spray Dried Dispersion (SDD) Formulation of CC-11050 After Single Dose of CC-11050 and to Evaluate the Pharmacokinetics of CC-11050 Under Fasted and Fed Conditions and After Coadministration With Omeprazole

A Phase 1 study, sponsored by Amgen.

Completed
Registry status
Phase 1
Development phase
44
Enrollment target

NCT04139226 is a Phase 1 study that has completed, run by Amgen. The registered enrollment target is 44 participants.

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The verdict

NCT04139226, a Phase 1 study, has completed, sponsored by Amgen.

COMPLETED
Registry status
Phase 1
Development phase
44 participants
Enrollment target

Study Summary

This is a two-part study to be conducted at single study center, (additional center(s) may be selected if needed) to assess the safety, tolerability, PK and PD parameters for a new SDD formulation of CC-11050 in healthy subjects. The effects of a high-fat meal and omeprazole will also be assessed. Blood samples will be collected at prespecified times for PK, clinical laboratory safety assessments, PD (Part 1 only), and/or exploratory analyses. Safety will be monitored throughout the study from the time the ICF is signed through study completion.

Interventions

  • DRUG CC-11050

Trial Details

FieldValue
Enrollment Target 44 participants
Start Date 2019-08-28
Est. Completion 2020-02-27
Phase Phase 1

Sponsor

Amgen

558 total trials

What the Registry Record Tells You About NCT04139226

The ClinicalTrials.gov registry entry for NCT04139226 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 44 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Amgen, which has 558 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which CC-11050 is the first listed.

NCT04139226 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04139226 about?

NCT04139226 is a clinical study titled "A Study to Evaluate the Safety, Tolerability Pharmacokinetics, and Pharmacodynamics of a New Spray Dried Dispersion (SDD) Formulation of CC-11050 After Single Dose of CC-11050 and to Evaluate the Pharmacokinetics of CC-11050 Under Fasted and Fed Conditions and After Coadministration With Omeprazole". This is a two-part study to be conducted at single study center, (additional center(s) may be selected if needed) to assess the safety, tolerability, PK and PD parameters for a new SDD formulation of CC-11050 in healthy subjects. The effects of a high-fat meal and omeprazole will also be assessed. B...

What is the current status of trial NCT04139226?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 44 participants. The study started on 2019-08-28. Estimated completion is 2020-02-27.

What interventions are being tested in trial NCT04139226?

The interventions under investigation include: CC-11050 (DRUG).

Who is sponsoring clinical trial NCT04139226?

This trial is sponsored by Amgen, which has 558 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.