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NCT04138953 · ClinicalTrials.gov registry record · NA
Cortical Contributions to Motor Sequence Learning
A NA study of Brain Injuries, sponsored by Emory University.
- Completed
- Registry status
- NA
- Development phase
- 64
- Enrollment target
- 2
- Study locations
NCT04138953: Completed NA study of Brain Injuries, sponsored by Emory University.
NCT04138953 is a NA study of Brain Injuries that has completed, run by Emory University. The registered enrollment target is 64 participants, below the 328-participant average among 22 other Brain Injuries trials with a reported enrollment target (80% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04138953, a NA study of Brain Injuries, has completed, sponsored by Emory University.
- COMPLETED
- Registry status
- NA
- Development phase
- 64 participants
- Enrollment target
- 2
- Study locations
Study Summary
The long-term objective initiated with this study is to determine which brain areas functionally contribute to learning a motor skill. The primary hypothesis of this trial is that premotor cortex (PMC) is necessary to learn a new motor skill. Participants may undergo a MRI scan to acquire a structural image of their brain to target noninvasive stimulation, using transcranial magnetic stimulation (TMS) to one of two brain areas: PMC or primary motor cortex (M1). A third group of individuals will undergo a placebo stimulation protocol. For all three groups, stimulation will be used to create a transient 'virtual lesion' during motor skill training. Temporarily disrupting the normal activity of these brain regions during training will allow us to determine which regions are causally involved in learning a new motor skill. The primary outcome measure will be the change in skill after training in each group.
Primary Outcome
The SRTT involves pressing a key that corresponds to a target square presented on a monitor. Sequenced skill (SS) is calculated by subtracting the response time of sequenced key presses from random key presses within and across a test block. An increase in SS value indicates an increase in sequenced skill and is a preferable result.
Conditions Studied
Interventions
- DEVICE Transcranial Magnetic Stimulation (TMS)
- OTHER Sham TMS
Study Locations (2)
Georgia
- Emory University - Atlanta
- Wesley Woods - Atlanta
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 64 participants |
| Start Date | 2019-12-05 |
| Est. Completion | 2023-08-04 |
| Phase | NA |
What the finished NCT04138953 record still lists
NCT04138953 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 64 participants, a relatively small participant target, below the 328-participant average among 22 other Brain Injuries trials with a reported enrollment target (80% lower).
The record links to 1 condition, with Brain Injuries appearing as the primary indexed condition, and to 2 interventions - of which Transcranial Magnetic Stimulation (TMS) is the first listed.
NCT04138953 reports a single indexed study location in Georgia.
Frequently Asked Questions
What is clinical trial NCT04138953 about?
NCT04138953 is a clinical study titled "Cortical Contributions to Motor Sequence Learning". The long-term objective initiated with this study is to determine which brain areas functionally contribute to learning a motor skill. The primary hypothesis of this trial is that premotor cortex (PMC) is necessary to learn a new motor skill. Participants may undergo a MRI scan to acquire a structur...
What is the current status of trial NCT04138953?
This trial is currently completed. It is a NA study. The enrollment target is 64 participants. The study started on 2019-12-05. Estimated completion is 2023-08-04.
What conditions does trial NCT04138953 study?
This clinical trial studies the following conditions: Brain Injuries.
What interventions are being tested in trial NCT04138953?
The interventions under investigation include: Transcranial Magnetic Stimulation (TMS) (DEVICE), Sham TMS (OTHER).
Who is sponsoring clinical trial NCT04138953?
This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04138953 being conducted?
This trial has 2 study locations across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Brain Injuries
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04138953's enrollment target sits among peer trials
64 15th of 22 higher than 8 of 22 other Brain Injuries trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Brain Injuries trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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