Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04135703 · ClinicalTrials.gov registry record · NA
Prevention of OUD: The HOME Project (Housing, Opportunities, Motivation and Engagement)
A NA study of Substance Use, sponsored by Ohio State University.
- Completed
- Registry status
- NA
- Development phase
- 240
- Enrollment target
- 1
- Study location
NCT04135703: Completed NA study of Substance Use, sponsored by Ohio State University.
NCT04135703 is a NA study of Substance Use that has completed, run by Ohio State University. The registered enrollment target is 240 participants, below the 1,258-participant average among 88 other Substance Use trials with a reported enrollment target (81% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04135703, a NA study of Substance Use, has completed, sponsored by Ohio State University.
- COMPLETED
- Registry status
- NA
- Development phase
- 240 participants
- Enrollment target
- 1
- Study location
Study Summary
Homeless youth have a much higher rate of substance use than non-homeless peers with evidence suggesting that homeless youth have the highest rates of opioid use among youth subgroups in the country (Brands et al., 2005); heroin using homeless youth also appear to have the highest rates of IV drug use and HIV (Rhoades et al., 2014). Given the high rates of opioid use, exposure to violence, mental and physical health challenges, and high rates of mortality in homeless youth, it is surprising that no study to date utilizes a randomized controlled design to test prevention of opioid and other drug use among this vulnerable population. Resolution of youth homelessness through housing and prevention services, often referred to as "Housing First", as proposed in the current study, has great potential to reduce the likelihood for the development of an opioid use disorder as well as other problem behaviors associated with living on the streets. However, only 20-30% of homeless youth samples report ever having stayed at a crisis shelter, 9% report having ever accessed mental health services, and 15% report ever having received substance use treatment (Ray, 2006) indicating a need to reach and engage youth in services that are feasible and acceptable. This study will provide essential information for researchers and providers on the efficacy of housing + opioid and related risk prevention services in an RCT on opioid use, how moderators affect the response, and mechanisms underlying change.
Primary Outcome
frequency (% days in prior 90) of opioid use is measured at baseline, 3, 6, 9 and 12 months post-baseline
Conditions Studied
Interventions
- BEHAVIORAL Risk Prevention Services + Housing
- BEHAVIORAL Risk Prevention Services Only
Study Locations (1)
Ohio
- The Ohio State University - Columbus
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 240 participants |
| Start Date | 2020-06-23 |
| Est. Completion | 2024-05-14 |
| Phase | NA |
What the finished NCT04135703 record still lists
NCT04135703 is an interventional study that assigns participants to a tested intervention. The registered 240 participants enrollment target is mid-sized for trials with a published cap, below the 1,258-participant average among 88 other Substance Use trials with a reported enrollment target (81% lower).
The record links to 1 condition, with Substance Use appearing as the primary indexed condition, and to 2 interventions - of which Risk Prevention Services + Housing is the first listed.
NCT04135703 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT04135703 about?
NCT04135703 is a clinical study titled "Prevention of OUD: The HOME Project (Housing, Opportunities, Motivation and Engagement)". Homeless youth have a much higher rate of substance use than non-homeless peers with evidence suggesting that homeless youth have the highest rates of opioid use among youth subgroups in the country (Brands et al., 2005); heroin using homeless youth also appear to have the highest rates of IV drug u...
What is the current status of trial NCT04135703?
This trial is currently completed. It is a NA study. The enrollment target is 240 participants. The study started on 2020-06-23. Estimated completion is 2024-05-14.
What conditions does trial NCT04135703 study?
This clinical trial studies the following conditions: Substance Use.
What interventions are being tested in trial NCT04135703?
The interventions under investigation include: Risk Prevention Services + Housing (BEHAVIORAL), Risk Prevention Services Only (BEHAVIORAL).
Who is sponsoring clinical trial NCT04135703?
This trial is sponsored by Ohio State University, which has 552 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04135703 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Substance Use
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04135703's enrollment target sits among peer trials
240 40th of 88 higher than 48 of 88 other Substance Use trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Substance Use trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Native Spirit: Significant Aim 3: Intervention
RECRUITING · NA
-
Parent SMART (Substance Misuse in Adolescents in Residential Treatment)
RECRUITING · NA
-
Cultural Adaptation of Drug Treatment for DJJ Youth
RECRUITING · NA
-
Adaptation and Evaluation of Bright Horizons
RECRUITING · NA
-
Teen Health Choices & Wellness
RECRUITING · NA
-
Pre-exposure Prophylaxis (PrEP) Uptake and Adherence Intervention for Women with Trauma-related Conditions
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02855554 · 240 participants · NA
Quantitative Cardiac Parametric Mapping
- NCT03230565 · 240 participants · Phase 4
Continuous Infusions vs Scheduled Bolus Infusions
- NCT03399929 · 240 participants
Traumatic Brain Injury and Stroke Long Term Outcome
- NCT03583710 · 240 participants · Phase 3
Mitotane With or Without Cisplatin and Etoposide After Surgery in Treating Patients With Stage I-III Adrenocortical Cancer With High Risk of Recurrence
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI