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NCT04133415 · ClinicalTrials.gov registry record · NA
Palliative Lattice Stereotactic Body Radiotherapy (SBRT)
A NA study, sponsored by Washington University School of Medicine.
- Completed
- Registry status
- NA
- Development phase
- 20
- Enrollment target
NCT04133415: Completed NA study, sponsored by Washington University School of Medicine.
NCT04133415 is a NA study that has completed, run by Washington University School of Medicine. The registered enrollment target is 20 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04133415, a NA study, has completed, sponsored by Washington University School of Medicine.
- COMPLETED
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
Study Summary
Standard palliative radiotherapy regimens may provide limited durability of response in large tumors. Thus, there is a clinical need for a new approach. The Lattice SBRT approach will deliver 20 Gy in 5 fractions with partial volume simultaneous integrated boosts to 66.7 Gy. This is hypothesized to improve symptom response, local control, and better prime the tumor microenvironment for immune response compared with standard palliative radiotherapy doses. It is also hypothesized that this will be associated with less toxicity than the traditional homogenous SBRT plan delivered to a large tumor. Blood will be collected before and after Lattice SBRT for evaluation of the peripheral blood immune microenvironment.
Primary Outcome
-Measured by CTCAE version 5.0
Interventions
- PROCEDURE Peripheral blood
- RADIATION Lattice stereotactic body radiation therapy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2019-10-31 |
| Est. Completion | 2020-12-14 |
| Phase | NA |
What the finished NCT04133415 record still lists
NCT04133415 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which Peripheral blood is the first listed.
NCT04133415 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04133415 about?
NCT04133415 is a clinical study titled "Palliative Lattice Stereotactic Body Radiotherapy (SBRT)". Standard palliative radiotherapy regimens may provide limited durability of response in large tumors. Thus, there is a clinical need for a new approach. The Lattice SBRT approach will deliver 20 Gy in 5 fractions with partial volume simultaneous integrated boosts to 66.7 Gy. This is hypothesized to ...
What is the current status of trial NCT04133415?
This trial is currently completed. It is a NA study. The enrollment target is 20 participants. The study started on 2019-10-31. Estimated completion is 2020-12-14.
What interventions are being tested in trial NCT04133415?
The interventions under investigation include: Peripheral blood (PROCEDURE), Lattice stereotactic body radiation therapy (RADIATION).
Who is sponsoring clinical trial NCT04133415?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04133415's enrollment target sits among peer trials
20 1768th of 2000 higher than 140 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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