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NCT04131595 · ClinicalTrials.gov registry record · Phase 1

Vaccination Trial of a Recombinant MVA-BN-WEV Vaccine in Healthy Adult Subjects

A Phase 1 study of Equine Encephalitis, sponsored by Bavarian Nordic.

Completed
Registry status
Phase 1
Development phase
45
Enrollment target
1
Study location

NCT04131595: Completed Phase 1 study of Equine Encephalitis, sponsored by Bavarian Nordic.

NCT04131595 is a Phase 1 study of Equine Encephalitis that has completed, run by Bavarian Nordic. The registered enrollment target is 45 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (25% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04131595, a Phase 1 study of Equine Encephalitis, has completed, sponsored by Bavarian Nordic.

COMPLETED
Registry status
Phase 1
Development phase
45 participants
Enrollment target
1
Study location

Study Summary

To assess safety and tolerability as well as immune responses to the MVA-BN-WEV vaccine in the 3 treatment groups receiving different doses.

Primary Outcome

Number of subjects reporting any serious adverse events (SAE)

Conditions Studied

Interventions

  • BIOLOGICAL MVA-BN-WEV Dose 1
  • BIOLOGICAL MVA-BN-WEV Dose 2
  • BIOLOGICAL MVA-BN-WEV Dose 3

Study Locations (1)

Kansas

  • Johnson County Clin-Trials - Lenexa

Trial Details

FieldValue
Enrollment Target 45 participants
Start Date 2019-10-07
Est. Completion 2020-07-22
Phase Phase 1
Bavarian Nordic

41 total trials

What the finished NCT04131595 record still lists

NCT04131595 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 45 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (25% lower).

The record links to 1 condition, with Equine Encephalitis appearing as the primary indexed condition, and to 3 interventions - of which MVA-BN-WEV Dose 1 is the first listed.

NCT04131595 reports a single indexed study location in Kansas.

Frequently Asked Questions

What is clinical trial NCT04131595 about?

NCT04131595 is a clinical study titled "Vaccination Trial of a Recombinant MVA-BN-WEV Vaccine in Healthy Adult Subjects". To assess safety and tolerability as well as immune responses to the MVA-BN-WEV vaccine in the 3 treatment groups receiving different doses.

What is the current status of trial NCT04131595?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 45 participants. The study started on 2019-10-07. Estimated completion is 2020-07-22.

What conditions does trial NCT04131595 study?

This clinical trial studies the following conditions: Equine Encephalitis.

What interventions are being tested in trial NCT04131595?

The interventions under investigation include: MVA-BN-WEV Dose 1 (BIOLOGICAL), MVA-BN-WEV Dose 2 (BIOLOGICAL), MVA-BN-WEV Dose 3 (BIOLOGICAL).

Who is sponsoring clinical trial NCT04131595?

This trial is sponsored by Bavarian Nordic, which has 41 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04131595 being conducted?

This trial has 1 study location across Kansas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

How this trial's enrollment target compares

Where NCT04131595's enrollment target sits among peer trials

45 1066th of 2000 higher than 915 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04131595, the US trial registry maintained by the National Library of Medicine. NCT04131595 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.