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NCT04129216 · ClinicalTrials.gov registry record · Phase 2
The Effects of Short-term Preoperative Treatment With Hormonal Therapy on Gene Profiles in Breast Cancer
A Phase 2 study, sponsored by Johns Hopkins University.
- Completed
- Registry status
- Phase 2
- Development phase
- 30
- Enrollment target
NCT04129216: Completed Phase 2 study, sponsored by Johns Hopkins University.
NCT04129216 is a Phase 2 study that has completed, run by Johns Hopkins University. The registered enrollment target is 30 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (77% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04129216, a Phase 2 study, has completed, sponsored by Johns Hopkins University.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 30 participants
- Enrollment target
Study Summary
The investigators would like to study the genetic and molecular outcomes that results after a short term neoadjuvant hormonal therapy on patients with breast cancer.
Primary Outcome
This is a measure of tumor proliferation, and will be determined at baseline and at time of surgery.
Interventions
- DRUG Letrozole
- DRUG Exemestane
- DRUG Tamoxifen Citrate
- DIAGNOSTIC_TEST Blueprint
- DIAGNOSTIC_TEST Mammaprint
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2019-02-20 |
| Est. Completion | 2022-11-10 |
| Phase | Phase 2 |
What the finished NCT04129216 record still lists
NCT04129216 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (77% lower).
The record links to 0 conditions, and to 5 interventions - of which Letrozole is the first listed.
NCT04129216 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04129216 about?
NCT04129216 is a clinical study titled "The Effects of Short-term Preoperative Treatment With Hormonal Therapy on Gene Profiles in Breast Cancer". The investigators would like to study the genetic and molecular outcomes that results after a short term neoadjuvant hormonal therapy on patients with breast cancer.
What is the current status of trial NCT04129216?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 30 participants. The study started on 2019-02-20. Estimated completion is 2022-11-10.
What interventions are being tested in trial NCT04129216?
The interventions under investigation include: Letrozole (DRUG), Exemestane (DRUG), Tamoxifen Citrate (DRUG), Blueprint (DIAGNOSTIC_TEST), Mammaprint (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT04129216?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04129216's enrollment target sits among peer trials
30 1582nd of 2000 higher than 332 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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