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NCT04127825 · ClinicalTrials.gov registry record · NA

Acute Normovolemic Hemodilution (ANH) in Patients Undergoing Cardiac Surgery

A NA study, sponsored by University of Minnesota.

Completed
Registry status
NA
Development phase
2
Enrollment target

NCT04127825 is a NA study that has completed, run by University of Minnesota. The registered enrollment target is 2 participants.

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The verdict

NCT04127825, a NA study, has completed, sponsored by University of Minnesota.

COMPLETED
Registry status
NA
Development phase
2 participants
Enrollment target

Study Summary

The purpose of this small randomized pilot study is to evaluate adherence to strict transfusion protocols in both the control and ANH group examining compliant and noncompliant transfusion rates and reasons for violation of the protocol if present. Data on transfusion requirements for both groups (with and without ANH) will be evaluated to determine sample size and feasibility of performing a larger study on ANH in our patient population. The ultimate purpose of a larger study would be to determine if acute normovolemic hemodilution results in a reduction in red blood cell units transfused in patients undergoing cardiac surgery involving cardiopulmonary bypass (CPB) and to carefully determine provider adherence to specific transfusion triggers for the administration of each unit of harvested and banked blood transfused. Secondary endpoints that will be evaluated in a larger study include any difference in the number of other blood products transfused including fresh frozen plasma, platelets, and cryoprecipitate as well as differences in coagulation status as measured by thromboelastography (TEG), INR/PTT, platelet count, and fibrinogen level, and ICU/hospital length of stay.

Interventions

  • PROCEDURE Acute Normovolemic Hemodilution (ANH)

Trial Details

FieldValue
Enrollment Target 2 participants
Start Date 2017-11-01
Est. Completion 2021-04-30
Phase NA

Sponsor

University of Minnesota

966 total trials

What the Registry Record Tells You About NCT04127825

The ClinicalTrials.gov registry entry for NCT04127825 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 2 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Minnesota, which has 966 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Acute Normovolemic Hemodilution (ANH) is the first listed.

NCT04127825 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04127825 about?

NCT04127825 is a clinical study titled "Acute Normovolemic Hemodilution (ANH) in Patients Undergoing Cardiac Surgery". The purpose of this small randomized pilot study is to evaluate adherence to strict transfusion protocols in both the control and ANH group examining compliant and noncompliant transfusion rates and reasons for violation of the protocol if present. Data on transfusion requirements for both groups (w...

What is the current status of trial NCT04127825?

This trial is currently completed. It is a NA study. The enrollment target is 2 participants. The study started on 2017-11-01. Estimated completion is 2021-04-30.

What interventions are being tested in trial NCT04127825?

The interventions under investigation include: Acute Normovolemic Hemodilution (ANH) (PROCEDURE).

Who is sponsoring clinical trial NCT04127825?

This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.