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NCT04117958 · ClinicalTrials.gov registry record · Phase 1
Study of AMG 199 in Subjects With MUC17-Positive Solid Tumors Including Gastric, Gastroesophageal Junction, Colorectal, and Pancreatic Cancers
A Phase 1 study, sponsored by Amgen.
- Terminated
- Registry status
- Phase 1
- Development phase
- 58
- Enrollment target
NCT04117958: Clinical Trial Phase 1 study, sponsored by Amgen.
NCT04117958 is a Phase 1 study that was terminated before completion, run by Amgen. The registered enrollment target is 58 participants, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04117958, a Phase 1 study, was terminated before completion, sponsored by Amgen.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 58 participants
- Enrollment target
Study Summary
To evaluate the safety and tolerability of AMG 199 in adult subjects and to determine the maximum tolerated dose (MTD) and/or recommended phase 2 dose (RP2D).
Primary Outcome
To evaluate the safety and tolerability of AMG 199 in adult subjects and to determine the maximum tolerated dose (MTD) and/or recommended phase 2 dose (RP2D).
Interventions
- DRUG AMG 199
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 58 participants |
| Start Date | 2020-01-20 |
| Est. Completion | 2023-06-01 |
| Phase | Phase 1 |
Why NCT04117958 stopped before completion
NCT04117958 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 58 participants, a relatively small participant target, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target.
The record links to 0 conditions, and to 1 intervention - of which AMG 199 is the first listed.
NCT04117958 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04117958 about?
NCT04117958 is a clinical study titled "Study of AMG 199 in Subjects With MUC17-Positive Solid Tumors Including Gastric, Gastroesophageal Junction, Colorectal, and Pancreatic Cancers". To evaluate the safety and tolerability of AMG 199 in adult subjects and to determine the maximum tolerated dose (MTD) and/or recommended phase 2 dose (RP2D).
What is the current status of trial NCT04117958?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 58 participants. The study started on 2020-01-20. Estimated completion is 2023-06-01.
What interventions are being tested in trial NCT04117958?
The interventions under investigation include: AMG 199 (DRUG).
Who is sponsoring clinical trial NCT04117958?
This trial is sponsored by Amgen, which has 558 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04117958's enrollment target sits among peer trials
58 895th of 2000 higher than 1,100 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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