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NCT04117542 · ClinicalTrials.gov registry record
Working Memory in Overweight Children With and Without Loss of Control Eating
A clinical trial of Pediatric Obesity and Binge Eating, sponsored by The Miriam Hospital.
- Completed
- Registry status
- 30
- Enrollment target
- 1
- Study location
NCT04117542: Completed study of Pediatric Obesity and Binge Eating, sponsored by The Miriam Hospital.
NCT04117542 is a study of Pediatric Obesity and Binge Eating that has completed, run by The Miriam Hospital. The registered enrollment target is 30 participants, below the 229-participant average among 45 other Pediatric Obesity trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04117542, a study of Pediatric Obesity and Binge Eating, has completed, sponsored by The Miriam Hospital.
- COMPLETED
- Registry status
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
Loss of control (LOC) eating in children is associated with multiple physical and mental health impairments, including obesity and eating disorders. Little is known about the developmental neurobiology of LOC, which is crucial to specifying its pathophysiology and the development of effective preventive interventions. Individual differences in working memory (WM) appear to be related to LOC eating and excess weight status in youth, but the specificity and neural correlates of these individual differences are unclear. Failure to adequately understand the nature of associations between WM and eating behavior in children with overweight/obesity limits the development of appropriately-targeted, neuro-developmentally informed interventions addressing problematic eating and related weight gain in youth. To close this clinical research gap, the current study proposes to investigate the context-dependence of WM impairment and its neural correlates in children with concomitant overweight/ obesity and LOC eating as compared to their overweight/obese peers. Specific aims are to investigate: 1)WM performance in youth with LOC eating relative to overweight/obese controls during recalls in the context of food-related versus neutral distractors; and 2) neural activation patterns during WM performance across both food-related and neutral stimuli. We hypothesize that, relative to their overweight/obese peers, youth with LOC eating will show 1) more errors and slower response times during recalls involving food-related vs. neutral distractors, and fewer errors and faster response times during recalls involving food-related vs. neutral targets; 2) increased activation in prefrontal regions during WM performance across stimuli types relative to overweight/obese controls, and 3) even greater activation in the context of food-related versus neutral distractors. The proposed study is the first to use state-of-the-science neuroimaging methodology to clarify the relations between WM and
Primary Outcome
Body Mass Index calculated with height/weight (cm/g)
Conditions Studied
Interventions
- OTHER Observational
Study Locations (1)
Rhode Island
- Weight Control & Diabetes Research Center - Providence
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2018-10-18 |
| Est. Completion | 2020-12-31 |
What the finished NCT04117542 record still lists
NCT04117542 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 229-participant average among 45 other Pediatric Obesity trials with a reported enrollment target (87% lower).
The record links to 2 conditions, with Pediatric Obesity appearing as the primary indexed condition, and to 1 intervention - of which Observational is the first listed.
NCT04117542 reports a single indexed study location in Rhode Island.
Frequently Asked Questions
What is clinical trial NCT04117542 about?
NCT04117542 is a clinical study titled "Working Memory in Overweight Children With and Without Loss of Control Eating". Loss of control (LOC) eating in children is associated with multiple physical and mental health impairments, including obesity and eating disorders. Little is known about the developmental neurobiology of LOC, which is crucial to specifying its pathophysiology and the development of effective preven...
What is the current status of trial NCT04117542?
This trial is currently completed. The enrollment target is 30 participants. The study started on 2018-10-18. Estimated completion is 2020-12-31.
What conditions does trial NCT04117542 study?
This clinical trial studies the following conditions: Pediatric Obesity, Binge Eating.
What interventions are being tested in trial NCT04117542?
The interventions under investigation include: Observational (OTHER).
Who is sponsoring clinical trial NCT04117542?
This trial is sponsored by The Miriam Hospital, which has 136 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04117542 being conducted?
This trial has 1 study location across Rhode Island. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04117542's enrollment target sits among peer trials
30 40th of 45 higher than 4 of 45 other Pediatric Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pediatric Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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