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NCT04112706 · ClinicalTrials.gov registry record · NA
Efficacy of CPP-ACP on Bleaching Related Sensitivity
A NA study, sponsored by University of New England.
- Completed
- Registry status
- NA
- Development phase
- 40
- Enrollment target
NCT04112706: Completed NA study, sponsored by University of New England.
NCT04112706 is a NA study that has completed, run by University of New England. The registered enrollment target is 40 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04112706, a NA study, has completed, sponsored by University of New England.
- COMPLETED
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
Study Summary
Objective: The purpose of this randomized controlled split-mouth clinical trial was to evaluate the effectiveness of MI paste in reducing sensitivity associated vital bleaching. Methods: 45 subjects were randomly divided into two groups, based upon which arch received MI Paste. Group 1 bleached Maxillary arch, Group 2 bleached mandibular arch. Two weeks later subjects stopped bleaching the first arch and started second arch. Sensitivity was measured by VAS daily log scale for two weeks. Shade was taken with colorimeter and Classic Vita shade guide at baseline, immediate post-bleaching, and two weeks post-bleaching. Longitudinal sensitivity over the 14 days period of bleaching was summarized. The Wilcoxon Signed Rank test was used to compare summary measures.
Primary Outcome
Thermal Sensitivity: Subjective Measure: Sensitivity was measured using thermal sensitivity scale (VAS) of 0-10, with 0 being "no pain" and 10 being "severe pain". Subjects were asked to pick a number. 2\. Objective Measure: Thermal sensitivity was measured by using a 1-second air blast at 700F from dental unit air syringe as per American Dental Association (ADA) guidelines. A Scale of 0-3 was used to measure the pain response with 0 indicating "no pain" and 3 indicating the "severe pain" whic
Interventions
- DRUG CPP-ACP
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2006-07-16 |
| Est. Completion | 2007-03-16 |
| Phase | NA |
What the finished NCT04112706 record still lists
NCT04112706 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 1 intervention - of which CPP-ACP is the first listed.
NCT04112706 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04112706 about?
NCT04112706 is a clinical study titled "Efficacy of CPP-ACP on Bleaching Related Sensitivity". Objective: The purpose of this randomized controlled split-mouth clinical trial was to evaluate the effectiveness of MI paste in reducing sensitivity associated vital bleaching. Methods: 45 subjects were randomly divided into two groups, based upon which arch received MI Paste. Group 1 bleached Max...
What is the current status of trial NCT04112706?
This trial is currently completed. It is a NA study. The enrollment target is 40 participants. The study started on 2006-07-16. Estimated completion is 2007-03-16.
What interventions are being tested in trial NCT04112706?
The interventions under investigation include: CPP-ACP (DRUG).
Who is sponsoring clinical trial NCT04112706?
This trial is sponsored by University of New England, which has 6 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04112706's enrollment target sits among peer trials
40 1447th of 2000 higher than 465 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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