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NCT04111497 · ClinicalTrials.gov registry record · Phase 1
Glasdegib for Chronic Graft-Versus-Host Disease
A Phase 1 study, sponsored by Fred Hutchinson Cancer Center.
- Terminated
- Registry status
- Phase 1
- Development phase
- 15
- Enrollment target
NCT04111497: Clinical Trial Phase 1 study, sponsored by Fred Hutchinson Cancer Center.
NCT04111497 is a Phase 1 study that was terminated before completion, run by Fred Hutchinson Cancer Center. The registered enrollment target is 15 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (75% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04111497, a Phase 1 study, was terminated before completion, sponsored by Fred Hutchinson Cancer Center.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 15 participants
- Enrollment target
Study Summary
This phase I/II trial studies whether glasdegib is helpful in treating sclerosis associated with chronic graft-versus-host disease. It will also investigate the safety of glasdegib in treating patients with chronic graft-versus-host disease.
Primary Outcome
Safety assessments will consist of monitoring and recording adverse events.
Interventions
- DRUG Glasdegib
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2019-12-03 |
| Est. Completion | 2023-08-23 |
| Phase | Phase 1 |
Why NCT04111497 stopped before completion
NCT04111497 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (75% lower).
The record links to 0 conditions, and to 1 intervention - of which Glasdegib is the first listed.
NCT04111497 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04111497 about?
NCT04111497 is a clinical study titled "Glasdegib for Chronic Graft-Versus-Host Disease". This phase I/II trial studies whether glasdegib is helpful in treating sclerosis associated with chronic graft-versus-host disease. It will also investigate the safety of glasdegib in treating patients with chronic graft-versus-host disease.
What is the current status of trial NCT04111497?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 15 participants. The study started on 2019-12-03. Estimated completion is 2023-08-23.
What interventions are being tested in trial NCT04111497?
The interventions under investigation include: Glasdegib (DRUG).
Who is sponsoring clinical trial NCT04111497?
This trial is sponsored by Fred Hutchinson Cancer Center, which has 483 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04111497's enrollment target sits among peer trials
15 1798th of 2000 higher than 157 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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