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NCT04096144 · ClinicalTrials.gov registry record · Phase 3

Comparison of Sugammadex and Neostigmine During PACU Stay

A Phase 3 study, sponsored by University of South Florida.

Not yet
Registry status
Phase 3
Development phase
50
Enrollment target

NCT04096144: Clinical Trial Phase 3 study, sponsored by University of South Florida.

NCT04096144 is a Phase 3 study that has not yet begun recruiting, run by University of South Florida. The registered enrollment target is 50 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04096144, a Phase 3 study, has not yet begun recruiting, sponsored by University of South Florida.

NOT YET RECRUITING
Registry status
Phase 3
Development phase
50 participants
Enrollment target

Study Summary

Sugammadex was approved for post-operative use in the operating room (OR) and post-anesthesia recovery unit (PACU) of our quaternary facility, Tampa General Hospital. The approval came with administrative limitations: 2mg/kg dose only and for the first year its utilization was limited as replacement for up to half of Neostigmine/Glycopyrrolate use. An MUE evaluation was completed for a retrospective chart review from March 2017 to December 2017 (10 months) to assess all cases in which patients received Sugammadex or Neostigmine. During the year of data collection, we also noted a widespread tendency to reduce the usage of narcotics. A t-test comparison of the length of stay (LOS) in the PACU revealed a highly significant difference between the LOS in PACU for both drugs. On average, patients receiving Sugammadex were discharged from the PACU 43 minutes earlier than patients who received Neostigmine/Glycopyrrolate. The patient mix in both groups was similar, but these data were obtained retrospectively by a pharmacy chart review.

Primary Outcome

Time spent in the recovery room (PACU).

Interventions

  • DRUG Neuromuscular Blocking Agents

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2019-10-15
Est. Completion 2020-06-15
Phase Phase 3
University of South Florida

252 total trials

What is known before NCT04096144 opens enrollment

NCT04096144 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (94% lower).

The record links to 0 conditions, and to 1 intervention - of which Neuromuscular Blocking Agents is the first listed.

NCT04096144 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04096144 about?

NCT04096144 is a clinical study titled "Comparison of Sugammadex and Neostigmine During PACU Stay". Sugammadex was approved for post-operative use in the operating room (OR) and post-anesthesia recovery unit (PACU) of our quaternary facility, Tampa General Hospital. The approval came with administrative limitations: 2mg/kg dose only and for the first year its utilization was limited as replacement...

What is the current status of trial NCT04096144?

This trial is currently not yet recruiting. It is a Phase 3 study. The enrollment target is 50 participants. The study started on 2019-10-15. Estimated completion is 2020-06-15.

What interventions are being tested in trial NCT04096144?

The interventions under investigation include: Neuromuscular Blocking Agents (DRUG).

Who is sponsoring clinical trial NCT04096144?

This trial is sponsored by University of South Florida, which has 252 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04096144's enrollment target sits among peer trials

50 1844th of 2000 higher than 141 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04096144, the US trial registry maintained by the National Library of Medicine. NCT04096144 (small enrollment · none site footprint · not yet recruiting) retrieved and formatted by PlainTrial, see methodology.