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NCT04090866 · ClinicalTrials.gov registry record

Cardiac Metabolic Remodeling After Pulmonary Vasodilator Therapy in Pulmonary Arterial Hypertension: A Pilot Study

A clinical trial, sponsored by University of Wisconsin, Madison.

Terminated
Registry status
2
Enrollment target

NCT04090866: Clinical Trial study, sponsored by University of Wisconsin, Madison.

NCT04090866 is a clinical trial that was terminated before completion, run by University of Wisconsin, Madison. The registered enrollment target is 2 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04090866 was terminated before completion, sponsored by University of Wisconsin, Madison.

TERMINATED
Registry status
2 participants
Enrollment target

Study Summary

Pulmonary arterial hypertension(PAH) is associated with the development of right heart failure. In the setting of heart failure, the heart shifts to increasing dependence on glucose metabolism. In this study, the investigators will perform cardiac positron emission tomography/magnetic resonance imaging (PET/MRI) scans to measure glucose metabolism in the heart before and after initiation of pulmonary vasodilator therapy for pulmonary arterial hypertension.

Primary Outcome

Substrate flexibility is defined as the change in myocardial to blood pool glucose uptake rate from rest to exercise.

Interventions

  • OTHER PET/MRI

Trial Details

FieldValue
Enrollment Target 2 participants
Start Date 2019-11-14
Est. Completion 2020-07-21
University of Wisconsin, Madison

1,039 total trials

Why NCT04090866 stopped before completion

NCT04090866 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 2 participants, a relatively small participant target.

The record links to 0 conditions, and to 1 intervention - of which PET/MRI is the first listed.

NCT04090866 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04090866 about?

NCT04090866 is a clinical study titled "Cardiac Metabolic Remodeling After Pulmonary Vasodilator Therapy in Pulmonary Arterial Hypertension: A Pilot Study". Pulmonary arterial hypertension(PAH) is associated with the development of right heart failure. In the setting of heart failure, the heart shifts to increasing dependence on glucose metabolism. In this study, the investigators will perform cardiac positron emission tomography/magnetic resonance imag...

What is the current status of trial NCT04090866?

This trial is currently terminated. The enrollment target is 2 participants. The study started on 2019-11-14. Estimated completion is 2020-07-21.

What interventions are being tested in trial NCT04090866?

The interventions under investigation include: PET/MRI (OTHER).

Who is sponsoring clinical trial NCT04090866?

This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.

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Source: ClinicalTrials.gov NCT04090866, the US trial registry maintained by the National Library of Medicine. NCT04090866 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.