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NCT04089501 · ClinicalTrials.gov registry record
The Role of the Pregnane X Receptor (PXR) in Indole Signaling and Intestinal Permeability in Inflammatory Bowel Disease
A clinical trial, sponsored by Albert Einstein College of Medicine.
- Completed
- Registry status
- 43
- Enrollment target
NCT04089501: Completed study, sponsored by Albert Einstein College of Medicine.
NCT04089501 is a clinical trial that has completed, run by Albert Einstein College of Medicine. The registered enrollment target is 43 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04089501 has completed, sponsored by Albert Einstein College of Medicine.
- COMPLETED
- Registry status
- 43 participants
- Enrollment target
Study Summary
The goal of this study is to better understand the mechanisms responsible for the development of and the severity of Inflammatory Bowel Disease (IBD), such as Crohn's Disease and Ulcerative Colitis, which cause inflammation of the gut as well as potentially affecting other areas of the body
Primary Outcome
We will measure and analyze RNA and protein levels of cytokines, junctional protein expression, PXR (pregnane X receptor) and TLRs (toll-like receptors) in tissues and perform intestinal permeability studies in subjects with and without IBD.
Interventions
- DIAGNOSTIC_TEST Stool collection
- DIAGNOSTIC_TEST Biopsy collection
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 43 participants |
| Start Date | 2015-02-25 |
| Est. Completion | 2019-05-02 |
What the finished NCT04089501 record still lists
NCT04089501 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 43 participants, a relatively small participant target.
The record links to 0 conditions, and to 2 interventions - of which Stool collection is the first listed.
NCT04089501 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04089501 about?
NCT04089501 is a clinical study titled "The Role of the Pregnane X Receptor (PXR) in Indole Signaling and Intestinal Permeability in Inflammatory Bowel Disease". The goal of this study is to better understand the mechanisms responsible for the development of and the severity of Inflammatory Bowel Disease (IBD), such as Crohn's Disease and Ulcerative Colitis, which cause inflammation of the gut as well as potentially affecting other areas of the body
What is the current status of trial NCT04089501?
This trial is currently completed. The enrollment target is 43 participants. The study started on 2015-02-25. Estimated completion is 2019-05-02.
What interventions are being tested in trial NCT04089501?
The interventions under investigation include: Stool collection (DIAGNOSTIC_TEST), Biopsy collection (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT04089501?
This trial is sponsored by Albert Einstein College of Medicine, which has 175 total clinical trials registered on ClinicalTrials.gov.
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