Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT04081636 · ClinicalTrials.gov registry record · NA

Prostate Biopsy, Transrectal vs. Transperineal: Efficacy and Complications

A NA study, sponsored by Albany Medical College.

Completed
Registry status
NA
Development phase
840
Enrollment target

NCT04081636: Completed NA study, sponsored by Albany Medical College.

NCT04081636 is a NA study that has completed, run by Albany Medical College. The registered enrollment target is 840 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (40% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT04081636, a NA study, has completed, sponsored by Albany Medical College.

COMPLETED
Registry status
NA
Development phase
840 participants
Enrollment target

Study Summary

This study evaluates the difference between 2 prostate biopsy methods, transrectal (through the rectal wall) and transperineal (through the skin) needle biopsy. Men who are in need of prostate biopsy due to clinical suspicions of prostate cancer will be randomly assigned (1:1) to either transrectal or transperineal approach. This research study will scientifically determine if one biopsy method is better than the other in reducing complications and improving cancer detection.

Primary Outcome

Whether or not patient had an infection after the biopsy

Interventions

  • PROCEDURE Systematic Transrectal biopsy (TR-Bx)
  • PROCEDURE Targeted Transrectal biopsy (TR-Bx)
  • PROCEDURE Systematic Transperineal biopsy (TP-Bx)
  • PROCEDURE Targeted Transperineal biopsy (TP-Bx)

Trial Details

FieldValue
Enrollment Target 840 participants
Start Date 2019-09-02
Est. Completion 2024-12-31
Phase NA
Albany Medical College

52 total trials

What the finished NCT04081636 record still lists

NCT04081636 is an interventional study that assigns participants to a tested intervention. The registered 840 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (40% lower).

The record links to 0 conditions, and to 4 interventions - of which Systematic Transrectal biopsy (TR-Bx) is the first listed.

NCT04081636 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04081636 about?

NCT04081636 is a clinical study titled "Prostate Biopsy, Transrectal vs. Transperineal: Efficacy and Complications". This study evaluates the difference between 2 prostate biopsy methods, transrectal (through the rectal wall) and transperineal (through the skin) needle biopsy. Men who are in need of prostate biopsy due to clinical suspicions of prostate cancer will be randomly assigned (1:1) to either transrectal...

What is the current status of trial NCT04081636?

This trial is currently completed. It is a NA study. The enrollment target is 840 participants. The study started on 2019-09-02. Estimated completion is 2024-12-31.

What interventions are being tested in trial NCT04081636?

The interventions under investigation include: Systematic Transrectal biopsy (TR-Bx) (PROCEDURE), Targeted Transrectal biopsy (TR-Bx) (PROCEDURE), Systematic Transperineal biopsy (TP-Bx) (PROCEDURE), Targeted Transperineal biopsy (TP-Bx) (PROCEDURE).

Who is sponsoring clinical trial NCT04081636?

This trial is sponsored by Albany Medical College, which has 52 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04081636's enrollment target sits among peer trials

840 133rd of 2000 higher than 1,867 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT04831580 · 840 participants · NA

    A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer

  • NCT04976881 · 840 participants · NA

    Promoting Preconception Care and Diabetes Self-Management Among Reproductive-Aged Women With Diabetes

  • NCT04985903 · 840 participants · NA

    Baby Steps III: Testing a Clinician and Patient Intervention to Promote Smoking Cessation Among Pregnant Women

  • NCT05384626 · 840 participants · Phase 1

    A Study of Neladalkib (NVL-655) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1)

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT04081636, the US trial registry maintained by the National Library of Medicine. NCT04081636 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.