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NCT04075721 · ClinicalTrials.gov registry record · Phase 1

First in Human Dose Escalation of M3258 as a Single Agent and Expansion Study of M3258 in Combination With Dexamethasone

A Phase 1 study, sponsored by EMD Serono Research & Development Institute.

Terminated
Registry status
Phase 1
Development phase
10
Enrollment target

NCT04075721 is a Phase 1 study that was terminated before completion, run by EMD Serono Research & Development Institute. The registered enrollment target is 10 participants.

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The verdict

NCT04075721, a Phase 1 study, was terminated before completion, sponsored by EMD Serono Research & Development Institute.

TERMINATED
Registry status
Phase 1
Development phase
10 participants
Enrollment target

Study Summary

The purpose of this study was to determine the safety, tolerability, pharmacokinetics, pharmacodynamics and early efficacy signs of M3258 as a single agent and co-administered with dexamethasone in participants with Relapsed Refractory Multiple Myeloma (RRMM).

Interventions

  • DRUG M3258
  • DRUG M3258 20 mg

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2019-09-26
Est. Completion 2021-04-01
Phase Phase 1

What the Registry Record Tells You About NCT04075721

The ClinicalTrials.gov registry entry for NCT04075721 describes a study currently listed as terminated, categorized as Phase 1. The registered enrollment target is 10 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is EMD Serono Research & Development Institute, which has 81 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which M3258 is the first listed.

NCT04075721 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04075721 about?

NCT04075721 is a clinical study titled "First in Human Dose Escalation of M3258 as a Single Agent and Expansion Study of M3258 in Combination With Dexamethasone". The purpose of this study was to determine the safety, tolerability, pharmacokinetics, pharmacodynamics and early efficacy signs of M3258 as a single agent and co-administered with dexamethasone in participants with Relapsed Refractory Multiple Myeloma (RRMM).

What is the current status of trial NCT04075721?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 10 participants. The study started on 2019-09-26. Estimated completion is 2021-04-01.

What interventions are being tested in trial NCT04075721?

The interventions under investigation include: M3258 (DRUG), M3258 20 mg (DRUG).

Who is sponsoring clinical trial NCT04075721?

This trial is sponsored by EMD Serono Research & Development Institute, which has 81 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.