Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04071951 · ClinicalTrials.gov registry record · NA
Pharmacist Intervention to Reduce Post-Hospitalization Utilization
A NA study of Polypharmacy and Nonadherence, Patient, sponsored by Cedars-Sinai Medical Center.
- Active
- Registry status
- NA
- Development phase
- 6,478
- Enrollment target
- 2
- Study locations
NCT04071951: Active NA study of Polypharmacy and Nonadherence, Patient, sponsored by Cedars-Sinai Medical Center.
NCT04071951 is a NA study of Polypharmacy and Nonadherence, Patient that is active but no longer recruiting, run by Cedars-Sinai Medical Center. The registered enrollment target is 6,478 participants, above the 941-participant average among 11 other Polypharmacy trials with a reported enrollment target (588% higher). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04071951, a NA study of Polypharmacy and Nonadherence, Patient, is active but no longer recruiting, sponsored by Cedars-Sinai Medical Center.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 6,478 participants
- Enrollment target
- 2
- Study locations
Study Summary
This is a randomized trial testing a peri- and post-discharge pharmacist-led medication management intervention on post-discharge utilization, including both readmissions and emergency department visits within 30 days of discharge. The intervention incorporates evidence addressing three main areas: medication reconciliation, medication adherence, and polypharmacy. This study uses a pragmatic trial randomized at the patient level and conducted in two large hospitals to achieve the following aims, each of which has been designed using the RE-AIM framework: Aim 1: To test the effect of PHARM-DC on post-discharge utilization among patients most at risk for post-discharge ADEs: recently discharged older adults taking \>10 medications or \>3 high-risk medications using a prospective, randomized, pragmatic multi-site study. Aim 2: To study barriers and facilitators of implementing PHARM-DC using a qualitative study. Aim 3: To analyze the costs of PHARM-DC, including the incremental cost per readmission averted and the net incremental cost from the health system perspective using a time-and-motion study and a cost-effectiveness analysis.
Primary Outcome
A patient is readmitted to a hospital (including observation) or has an ED visit within 30 days of discharge (including all hospitals at least statewide), excluding foreseen readmissions, which include: transplants, chemotherapy or radiotherapy, treatment follow-up, rehabilitation care, and planned operations
Conditions Studied
Interventions
- BEHAVIORAL Pharmacist-led Hospital Discharge Care Intervention
Study Locations (2)
California
- Cedars-Sinai Medical Center - Los Angeles
Massachusetts
- Brigham and Women's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 6,478 participants |
| Start Date | 2019-12-23 |
| Est. Completion | 2026-01-15 |
| Phase | NA |
What the registry record for NCT04071951 still lists
NCT04071951 is an interventional study that assigns participants to a tested intervention. Its 6,478 participants enrollment target places it among the larger protocols in the corpus, above the 941-participant average among 11 other Polypharmacy trials with a reported enrollment target (588% higher).
The record links to 3 conditions, with Polypharmacy appearing as the primary indexed condition, and to 1 intervention - of which Pharmacist-led Hospital Discharge Care Intervention is the first listed.
NCT04071951 reports a single indexed study location in California, Massachusetts.
Frequently Asked Questions
What is clinical trial NCT04071951 about?
NCT04071951 is a clinical study titled "Pharmacist Intervention to Reduce Post-Hospitalization Utilization". This is a randomized trial testing a peri- and post-discharge pharmacist-led medication management intervention on post-discharge utilization, including both readmissions and emergency department visits within 30 days of discharge. The intervention incorporates evidence addressing three main areas: ...
What is the current status of trial NCT04071951?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 6,478 participants. The study started on 2019-12-23. Estimated completion is 2026-01-15.
What conditions does trial NCT04071951 study?
This clinical trial studies the following conditions: Polypharmacy, Nonadherence, Patient, Readmission.
What interventions are being tested in trial NCT04071951?
The interventions under investigation include: Pharmacist-led Hospital Discharge Care Intervention (BEHAVIORAL).
Who is sponsoring clinical trial NCT04071951?
This trial is sponsored by Cedars-Sinai Medical Center, which has 339 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04071951 being conducted?
This trial has 2 study locations across California, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Polypharmacy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04071951's enrollment target sits among peer trials
6,478 1st of 11 higher than 11 of 11 other Polypharmacy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Polypharmacy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Improving Medication Management in World Trade Center Responders
RECRUITING · NA
-
The Geriatric Emergency Department Pharmacologic Harm Prevention Project
RECRUITING · NA
-
Effectiveness of PGx Testing
ACTIVE NOT RECRUITING · NA
-
Reducing High-Risk Geriatric Polypharmacy Via EHR Nudges R01 Trial
ACTIVE NOT RECRUITING · NA
-
Preemptive Pharmacogenomics Testing Among Geriatric Patients
ACTIVE NOT RECRUITING · NA
-
A Randomized Controlled Trial to Deprescribe for Older Patients With Polypharmacy
COMPLETED · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00505245 · 6,500 participants
New Assessment System in Measuring Symptom Distress in Cancer Patients
- NCT06821009 · 6,500 participants · NA
Effectiveness of a Cloud-based Digital Health Navigation Program for Colorectal Cancer Screening
- NCT05369429 · 6,516 participants · NA
My Wellbeing Guide: a Novel Tool for Managing Stress and Improving Quality of Life
- NCT05143697 · 6,600 participants · NA
Motivational Wellness Coaching to Reduce Childhood Obesity in Families and Kids
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI