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NCT04071548 · ClinicalTrials.gov registry record · NA
The Effect of Exercise on Muscle Dysfunction in Cystinosis
A NA study, sponsored by Stanford University.
- Completed
- Registry status
- NA
- Development phase
- 9
- Enrollment target
NCT04071548: Completed NA study, sponsored by Stanford University.
NCT04071548 is a NA study that has completed, run by Stanford University. The registered enrollment target is 9 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04071548, a NA study, has completed, sponsored by Stanford University.
- COMPLETED
- Registry status
- NA
- Development phase
- 9 participants
- Enrollment target
Study Summary
Classification of activity tolerance is of importance in chronic progressive myopathies, not only to better understand functional implications of the disease state itself, but also for purposes of exercise prescription for health maintenance. Maximal exercise testing has been considered as the gold standard of assessing maximal aerobic capacity, however testing in individuals with neuromuscular disease is often limited due to pain, activity intolerance, musculoskeletal impairments, fatigue and other such related variables. Often, submaximal exercise testing can overcome some of these obstacles, and as such, is used frequently in the clinical environment. Non-ambulatory exercise testing utilizing an arm ergometer specifically has not been studied as heavily, especially in those with progressive myopathies. For this study, we will use maximal aerobic capacity testing for individuals with Cystinosis Myopathy utilizing a bike ergometer to allow testing of individuals regardless of their ambulatory status.
Primary Outcome
Patients will undergo exercise stress testing using a recumbent cycle ergometry pre and post exercise intervention: Baseline and after week 12. We will use a ramping protocol to maintain a pedal cadence between 50-80RPM which will yield progressive workload increments of 5-10 Watts. Participants will be continuously monitored for any discomfort or pain that they may experience. Maximal effort will be verified as volitional fatigue (OMNI Scale≥8, the inability to maintain pedal cadence at 50 rpm
Interventions
- OTHER HIIT Exercise
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2023-01-26 |
| Est. Completion | 2024-05-15 |
| Phase | NA |
What the finished NCT04071548 record still lists
NCT04071548 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which HIIT Exercise is the first listed.
NCT04071548 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04071548 about?
NCT04071548 is a clinical study titled "The Effect of Exercise on Muscle Dysfunction in Cystinosis". Classification of activity tolerance is of importance in chronic progressive myopathies, not only to better understand functional implications of the disease state itself, but also for purposes of exercise prescription for health maintenance. Maximal exercise testing has been considered as the gold ...
What is the current status of trial NCT04071548?
This trial is currently completed. It is a NA study. The enrollment target is 9 participants. The study started on 2023-01-26. Estimated completion is 2024-05-15.
What interventions are being tested in trial NCT04071548?
The interventions under investigation include: HIIT Exercise (OTHER).
Who is sponsoring clinical trial NCT04071548?
This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04071548's enrollment target sits among peer trials
9 1975th of 2000 higher than 25 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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