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NCT04069026 · ClinicalTrials.gov registry record · Phase 1

A First-in-Humans Dose Finding Study for an Aryl Hydrocarbon Receptor Inhibitor (AhRi) in Patients With Advanced Cancer

A Phase 1 study, sponsored by Bayer.

Completed
Registry status
Phase 1
Development phase
78
Enrollment target

NCT04069026 is a Phase 1 study that has completed, run by Bayer. The registered enrollment target is 78 participants.

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The verdict

NCT04069026, a Phase 1 study, has completed, sponsored by Bayer.

COMPLETED
Registry status
Phase 1
Development phase
78 participants
Enrollment target

Study Summary

In this study researchers want to gather relevant information regarding the safety of BAY2416964 and how well the drug works in participants with a type of solid tumors that cannot be cured by currently available drugs. Researchers want to find the highest dose of BAY2416964 that participants could take without having too many side effects, how the drug is tolerated and the way the body absorbs, distributes and gets rid of the study dug. BAY2416964 is a small molecule which blocks the Aryl Hydrocarbon Receptor (a protein involved in immune cell reaction to tumor cells) allowing the body to use its immune response against the tumor cells.

Interventions

  • DRUG BAY2416964

Trial Details

FieldValue
Enrollment Target 78 participants
Start Date 2019-08-15
Est. Completion 2024-01-17
Phase Phase 1

Sponsor

Bayer

591 total trials

What the Registry Record Tells You About NCT04069026

The ClinicalTrials.gov registry entry for NCT04069026 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 78 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Bayer, which has 591 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which BAY2416964 is the first listed.

NCT04069026 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04069026 about?

NCT04069026 is a clinical study titled "A First-in-Humans Dose Finding Study for an Aryl Hydrocarbon Receptor Inhibitor (AhRi) in Patients With Advanced Cancer". In this study researchers want to gather relevant information regarding the safety of BAY2416964 and how well the drug works in participants with a type of solid tumors that cannot be cured by currently available drugs. Researchers want to find the highest dose of BAY2416964 that participants could ...

What is the current status of trial NCT04069026?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 78 participants. The study started on 2019-08-15. Estimated completion is 2024-01-17.

What interventions are being tested in trial NCT04069026?

The interventions under investigation include: BAY2416964 (DRUG).

Who is sponsoring clinical trial NCT04069026?

This trial is sponsored by Bayer, which has 591 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.