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NCT04064528 · ClinicalTrials.gov registry record · NA
Effects of Age on Amino Acid Delivery to Tendon
A NA study, sponsored by Purdue University.
- Completed
- Registry status
- NA
- Development phase
- 20
- Enrollment target
NCT04064528: Completed NA study, sponsored by Purdue University.
NCT04064528 is a NA study that has completed, run by Purdue University. The registered enrollment target is 20 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04064528, a NA study, has completed, sponsored by Purdue University.
- COMPLETED
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
Study Summary
Dietary amino acid supplementation may provide an effective means to promote tendon injury recovery and enhance collagen synthesis. While most published research has been completed in animal models, research with young adults has shown that a leucine-rich whey isolate consumed during a chronic resistance training (RT) intervention resulted in greater gains (\~60%) in tendon CSA when compared to placebo. Leucine-rich diets have also improved tendon collagen content in rodents. Further, in our preliminary work utilizing microdialysis, we demonstrate that oral consumption of a leucine-rich amino acid beverage increased delivery of amino acids to tendons in young adults (21-30 years). However, whether aging alters the delivery of amino acids to tendons after oral consumption has not be investigated. In order to optimize amino acid dosing for chronic interventional studies, we wish to determine if aging influences amino acid concentration in the peritendinous (space around the tendon) space after oral consumption.
Primary Outcome
Concentrations of amino acids will be measured from around the Achilles tendon
Interventions
- DIETARY_SUPPLEMENT Amino Acids
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2019-09-06 |
| Est. Completion | 2023-08-01 |
| Phase | NA |
What the finished NCT04064528 record still lists
NCT04064528 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which Amino Acids is the first listed.
NCT04064528 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04064528 about?
NCT04064528 is a clinical study titled "Effects of Age on Amino Acid Delivery to Tendon". Dietary amino acid supplementation may provide an effective means to promote tendon injury recovery and enhance collagen synthesis. While most published research has been completed in animal models, research with young adults has shown that a leucine-rich whey isolate consumed during a chronic resis...
What is the current status of trial NCT04064528?
This trial is currently completed. It is a NA study. The enrollment target is 20 participants. The study started on 2019-09-06. Estimated completion is 2023-08-01.
What interventions are being tested in trial NCT04064528?
The interventions under investigation include: Amino Acids (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT04064528?
This trial is sponsored by Purdue University, which has 141 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04064528's enrollment target sits among peer trials
20 1768th of 2000 higher than 140 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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