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NCT04063488 · ClinicalTrials.gov registry record

The Effects of Metreleptin in Congenital Leptin Deficiency

A clinical trial, sponsored by Northwestern University.

Completed
Registry status
2
Enrollment target

NCT04063488 is a clinical trial that has completed, run by Northwestern University. The registered enrollment target is 2 participants.

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The verdict

NCT04063488 has completed, sponsored by Northwestern University.

COMPLETED
Registry status
2 participants
Enrollment target

Study Summary

This study has been designed to 1) provide access to metreleptin to the only two individuals in the US known to have congenital leptin deficiency (CLD) and 2) explore a variety of unanswered questions about leptin physiology in general and metreleptin therapy in CLD specifically. The primary study endpoints include the following measures: body composition, measures of hepatic steatosis, measures of insulin sensitivity, and measures of sleep architecture. Secondary study endpoints include assessment of clock gene expression, body temperature, thyroid function, gonadal function, cognitive function, eating behavior, physical activity, mood, quality of life, and body image.

Interventions

  • DRUG Metreleptin

Trial Details

FieldValue
Enrollment Target 2 participants
Start Date 2019-06-20
Est. Completion 2021-08-13

Sponsor

Northwestern University

1,209 total trials

What the Registry Record Tells You About NCT04063488

The ClinicalTrials.gov registry entry for NCT04063488 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 2 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Northwestern University, which has 1,209 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Metreleptin is the first listed.

NCT04063488 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04063488 about?

NCT04063488 is a clinical study titled "The Effects of Metreleptin in Congenital Leptin Deficiency". This study has been designed to 1) provide access to metreleptin to the only two individuals in the US known to have congenital leptin deficiency (CLD) and 2) explore a variety of unanswered questions about leptin physiology in general and metreleptin therapy in CLD specifically. The primary study ...

What is the current status of trial NCT04063488?

This trial is currently completed. The enrollment target is 2 participants. The study started on 2019-06-20. Estimated completion is 2021-08-13.

What interventions are being tested in trial NCT04063488?

The interventions under investigation include: Metreleptin (DRUG).

Who is sponsoring clinical trial NCT04063488?

This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.