Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

ACTIVE NOT RECRUITING

Predicting Responsiveness in Oncology Patients Based on Host Response Evaluation During Anti Cancer Treatments

NCT04056247 · View on ClinicalTrials.gov ↗

Study Summary

The PROPHETIC study is a prospective, multi-center, international clinical study aimed at developing an algorithm to predict patient outcomes. The study involves analyzing the proteomic profiles of patients undergoing therapy to assess the likelihood of clinical benefit from their prescribed treatment. Blood samples are collected prior to and during the treatment period and analyzed as part of the ongoing development of thealgorithm.

Interventions

  • OTHER Plasma sample collection

Study Locations (20)

Other

  • Asklepois — Gauting
  • Thoraxklinik Heidelberg gGmbH — Heidelberg
  • Haemek Medical Center — Afula
  • Barzilai Medical Center — Ashkelon
  • Soroka Medical Center — Beersheba
  • Shamir Medical Center — Be’er Ya‘aqov
  • Bnai Zion Medical Center — Haifa
  • Rambam Medical Center — Haifa

Florida

  • Mayo Clinic — Jacksonville
  • University of Miami — Miami
  • Florida Cancer Specialist and Research Institute — Orlando
  • Protean Biodiagnosics — Orlando

Texas

  • Michael E. Debakey VA Medical Center — Houston
  • 151-Christus Health St. Michael — Texarkana

Alabama

  • Birmingham VAHCS — Birmingham

Illinois

  • Northwest Community Healthcare — Rolling Meadows

Iowa

  • Helen Nassif Community Cancer Center — Cedar Rapids

New Jersey

  • Rutgers Cancer Institute — New Brunswick

New York

  • Roswell Park — Buffalo

Trial Details

FieldValue
Enrollment Target 10,000 participants
Start Date 2019-10-01
Est. Completion 2029-10-01

Sponsor

OncoHost

2 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT04056247

The ClinicalTrials.gov registry entry for NCT04056247 describes a study currently listed as active not recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 10,000 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is OncoHost, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 5 conditions, with Stage IV Non-small Cell Lung Cancer appearing as the primary indexed condition, and to 1 intervention — of which Plasma sample collection is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT04056247 reports 20 study locations spanning 9 distinct geographic areas — top geographies include Other, Florida, Texas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT04056247 about?

NCT04056247 is a clinical study titled "Predicting Responsiveness in Oncology Patients Based on Host Response Evaluation During Anti Cancer Treatments". The PROPHETIC study is a prospective, multi-center, international clinical study aimed at developing an algorithm to predict patient outcomes. The study involves analyzing the proteomic profiles of patients undergoing therapy to assess the likelihood of clinical benefit from their prescribed treatme...

What is the current status of trial NCT04056247?

This trial is currently active not recruiting. The enrollment target is 10,000 participants. The study started on 2019-10-01. Estimated completion is 2029-10-01.

What conditions does trial NCT04056247 study?

This clinical trial studies the following conditions: Stage IV Non-small Cell Lung Cancer, Stage IV Small Cell Lung Cancer, Stage IV Malignant Melanoma, Stage III Unresectable Non-Small Cell Lung Cancer, Stage IIIb-d Malignant Melanoma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT04056247?

The interventions under investigation include: Plasma sample collection (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT04056247?

This trial is sponsored by OncoHost, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT04056247 being conducted?

This trial has 20 study locations across Alabama, Florida, Illinois, Iowa, New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial