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NCT04053075 · ClinicalTrials.gov registry record · NA
CLUSTER Trial for Outbreak Detection and Response
A NA study of Cluster Detection, sponsored by Harvard Pilgrim Health Care.
- Completed
- Registry status
- NA
- Development phase
- 2,905,455
- Enrollment target
- 20
- Study locations
NCT04053075: Completed NA study of Cluster Detection, sponsored by Harvard Pilgrim Health Care.
NCT04053075 is a NA study of Cluster Detection that has completed, run by Harvard Pilgrim Health Care. The registered enrollment target is 2,905,455 participants, above the 1,354-participant average among 58,714 other NA trials with a reported enrollment target (214483% higher). The trial reports 20 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04053075, a NA study of Cluster Detection, has completed, sponsored by Harvard Pilgrim Health Care.
- COMPLETED
- Registry status
- NA
- Development phase
- 2,905,455 participants
- Enrollment target
- 20
- Study locations
Study Summary
Despite the critical importance of identifying hospital-associated outbreaks as early as possible in order to limit their spread, there are currently no standardized methods for cluster detection. The CLUSTER Trial (Cluster Linkage Using Statistics to Trigger and Evaluate Response) will assess whether a statistically-based automated cluster detection method coupled with a robust response protocol will enable rapid containment of hospital clusters as measured by a reduction in cluster size and duration as compared to routine hospital cluster detection methods coupled with the same response protocol. Note: that enrolled "subjects" represents 82 individual HCA Healthcare hospitals that have been randomized
Primary Outcome
Cluster size defined as number of cases identified after the initial cluster signal through the last cluster case. NOTE: this outcome is intended for the primary manuscript.
Conditions Studied
Interventions
- OTHER Routine cluster detection
- OTHER Enhanced cluster detection
Study Locations (20)
Florida
- JFK Medical Center - Atlantis
- Brandon Regional - Brandon
- Lawnwood Regional Medical Center - Ft. Pierce
- Memorial Hospital Jacksonville - Jacksonville
- Lake City Medical Center - Lake City
- Largo Medical Center - Largo
- Ocala Regional Medical Center - Ocala
- West Marion Community Hospital - Ocala
- Raulerson Hospital - Okeechobee
- Orange Park Medical Center - Orange Park
- Gulf Coast Medical Center - Panama City
- West Florida Hospital - Pensacola
Colorado
- Swedish Medical Center - Denver
- Sky Ridge Medical Center - Denver
- Presbyterian St. Luke's Medical Center - Denver
- Rose Medical Center - Denver
- North Suburban Medical Center - JV - Thornton
California
- Riverside Community Hospital - Riverside
- Regional Medical Center of San Jose - San Jose
- Los Robles Regional Medical Center - Thousand Oaks
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,905,455 participants |
| Start Date | 2019-07-23 |
| Est. Completion | 2024-05-20 |
| Phase | NA |
What the finished NCT04053075 record still lists
NCT04053075 is an interventional study that assigns participants to a tested intervention. Its 2,905,455 participants enrollment target places it among the larger protocols in the corpus, above the 1,354-participant average among 58,714 other NA trials with a reported enrollment target (214483% higher).
The record links to 1 condition, with Cluster Detection appearing as the primary indexed condition, and to 2 interventions - of which Routine cluster detection is the first listed.
NCT04053075 names 20 study sites across 3 states, led by Florida, Colorado, California.
Frequently Asked Questions
What is clinical trial NCT04053075 about?
NCT04053075 is a clinical study titled "CLUSTER Trial for Outbreak Detection and Response". Despite the critical importance of identifying hospital-associated outbreaks as early as possible in order to limit their spread, there are currently no standardized methods for cluster detection. The CLUSTER Trial (Cluster Linkage Using Statistics to Trigger and Evaluate Response) will assess wheth...
What is the current status of trial NCT04053075?
This trial is currently completed. It is a NA study. The enrollment target is 2,905,455 participants. The study started on 2019-07-23. Estimated completion is 2024-05-20.
What conditions does trial NCT04053075 study?
This clinical trial studies the following conditions: Cluster Detection.
What interventions are being tested in trial NCT04053075?
The interventions under investigation include: Routine cluster detection (OTHER), Enhanced cluster detection (OTHER).
Who is sponsoring clinical trial NCT04053075?
This trial is sponsored by Harvard Pilgrim Health Care, which has 28 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04053075 being conducted?
This trial has 20 study locations across California, Colorado, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04053075's enrollment target sits among peer trials
2,905,455 1st of 2000 higher than 2,000 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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