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CLUSTER Trial for Outbreak Detection and Response
NCT04053075 · View on ClinicalTrials.gov ↗
Study Summary
Despite the critical importance of identifying hospital-associated outbreaks as early as possible in order to limit their spread, there are currently no standardized methods for cluster detection. The CLUSTER Trial (Cluster Linkage Using Statistics to Trigger and Evaluate Response) will assess whether a statistically-based automated cluster detection method coupled with a robust response protocol will enable rapid containment of hospital clusters as measured by a reduction in cluster size and duration as compared to routine hospital cluster detection methods coupled with the same response protocol. Note: that enrolled "subjects" represents 82 individual HCA Healthcare hospitals that have been randomized
Conditions Studied
Interventions
- OTHER Routine cluster detection
- OTHER Enhanced cluster detection
Study Locations (20)
Florida
- JFK Medical Center — Atlantis
- Brandon Regional — Brandon
- Lawnwood Regional Medical Center — Ft. Pierce
- Memorial Hospital Jacksonville — Jacksonville
- Lake City Medical Center — Lake City
- Largo Medical Center — Largo
- Ocala Regional Medical Center — Ocala
- West Marion Community Hospital — Ocala
- Raulerson Hospital — Okeechobee
- Orange Park Medical Center — Orange Park
- Gulf Coast Medical Center — Panama City
- West Florida Hospital — Pensacola
Colorado
- Swedish Medical Center — Denver
- Sky Ridge Medical Center — Denver
- Presbyterian St. Luke's Medical Center — Denver
- Rose Medical Center — Denver
- North Suburban Medical Center - JV — Thornton
California
- Riverside Community Hospital — Riverside
- Regional Medical Center of San Jose — San Jose
- Los Robles Regional Medical Center — Thousand Oaks
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,905,455 participants |
| Start Date | 2019-07-23 |
| Est. Completion | 2024-05-20 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04053075
The ClinicalTrials.gov registry entry for NCT04053075 describes a study currently listed as completed. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 2,905,455 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Harvard Pilgrim Health Care, which has 10 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Cluster Detection appearing as the primary indexed condition, and to 2 interventions — of which Routine cluster detection is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT04053075 reports 20 study locations spanning 3 distinct geographic areas — top geographies include Florida, Colorado, California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT04053075 about?
NCT04053075 is a clinical study titled "CLUSTER Trial for Outbreak Detection and Response". Despite the critical importance of identifying hospital-associated outbreaks as early as possible in order to limit their spread, there are currently no standardized methods for cluster detection. The CLUSTER Trial (Cluster Linkage Using Statistics to Trigger and Evaluate Response) will assess wheth...
What is the current status of trial NCT04053075?
This trial is currently completed. It is a NA study. The enrollment target is 2,905,455 participants. The study started on 2019-07-23. Estimated completion is 2024-05-20.
What conditions does trial NCT04053075 study?
This clinical trial studies the following conditions: Cluster Detection. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT04053075?
The interventions under investigation include: Routine cluster detection (OTHER), Enhanced cluster detection (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT04053075?
This trial is sponsored by Harvard Pilgrim Health Care, which has 10 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT04053075 being conducted?
This trial has 20 study locations across California, Colorado, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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