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NCT04048681 · ClinicalTrials.gov registry record · NA

Neurological Impacts of Artificial Sweeteners in the Context of Diet Sodas

A NA study, sponsored by Beth Israel Deaconess Medical Center.

Completed
Registry status
NA
Development phase
5
Enrollment target

NCT04048681: Completed NA study, sponsored by Beth Israel Deaconess Medical Center.

NCT04048681 is a NA study that has completed, run by Beth Israel Deaconess Medical Center. The registered enrollment target is 5 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04048681, a NA study, has completed, sponsored by Beth Israel Deaconess Medical Center.

COMPLETED
Registry status
NA
Development phase
5 participants
Enrollment target

Study Summary

This study seeks to determine whether artificial sweeteners in the context of diet soda may alter the brain's response to food cues and thus impact appetite.

Primary Outcome

Functional magnetic resonance imaging (BOLD signals) while patients view food vs. non-food cues. The effect size z-score represents the magnitude of the activation in that area to food cues vs. non-food cues. The z-score is the estimated response magnitude in that area compared to the overall mean. Negative numbers indicate values lower than the mean and positive numbers indicate values above the mean.

Interventions

  • BEHAVIORAL Regular soda
  • BEHAVIORAL diet soda
  • BEHAVIORAL Carbonated Water

Trial Details

FieldValue
Enrollment Target 5 participants
Start Date 2019-08-06
Est. Completion 2019-12-20
Phase NA

What the finished NCT04048681 record still lists

NCT04048681 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).

The record links to 0 conditions, and to 3 interventions - of which Regular soda is the first listed.

NCT04048681 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04048681 about?

NCT04048681 is a clinical study titled "Neurological Impacts of Artificial Sweeteners in the Context of Diet Sodas". This study seeks to determine whether artificial sweeteners in the context of diet soda may alter the brain's response to food cues and thus impact appetite.

What is the current status of trial NCT04048681?

This trial is currently completed. It is a NA study. The enrollment target is 5 participants. The study started on 2019-08-06. Estimated completion is 2019-12-20.

What interventions are being tested in trial NCT04048681?

The interventions under investigation include: Regular soda (BEHAVIORAL), diet soda (BEHAVIORAL), Carbonated Water (BEHAVIORAL).

Who is sponsoring clinical trial NCT04048681?

This trial is sponsored by Beth Israel Deaconess Medical Center, which has 488 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04048681's enrollment target sits among peer trials

5 1988th of 2000 higher than 5 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04048681, the US trial registry maintained by the National Library of Medicine. NCT04048681 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.