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NCT04039087 · ClinicalTrials.gov registry record · Phase 2

Sildenafil Exercise: Role of PDE5 Inhibition

A Phase 2 study, sponsored by National Jewish Health.

Completed
Registry status
Phase 2
Development phase
26
Enrollment target

NCT04039087 is a Phase 2 study that has completed, run by National Jewish Health. The registered enrollment target is 26 participants.

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The verdict

NCT04039087, a Phase 2 study, has completed, sponsored by National Jewish Health.

COMPLETED
Registry status
Phase 2
Development phase
26 participants
Enrollment target

Study Summary

Exercise intolerance is an understudied phenomenon in people with CF. The investigators hypothesized that vascular dysfunction plays a significant role, and can be partially reversed by administration of the phosphodiesterase type 5 (PDE5) inhibitor, sildenafil.

Interventions

  • DRUG Sildenafil 40mg oral capsule
  • DRUG Placebo Oral capsule

Trial Details

FieldValue
Enrollment Target 26 participants
Start Date 2019-09-05
Est. Completion 2024-06-30
Phase Phase 2

Sponsor

National Jewish Health

83 total trials

What the Registry Record Tells You About NCT04039087

The ClinicalTrials.gov registry entry for NCT04039087 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 26 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Jewish Health, which has 83 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Sildenafil 40mg oral capsule is the first listed.

NCT04039087 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04039087 about?

NCT04039087 is a clinical study titled "Sildenafil Exercise: Role of PDE5 Inhibition". Exercise intolerance is an understudied phenomenon in people with CF. The investigators hypothesized that vascular dysfunction plays a significant role, and can be partially reversed by administration of the phosphodiesterase type 5 (PDE5) inhibitor, sildenafil.

What is the current status of trial NCT04039087?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 26 participants. The study started on 2019-09-05. Estimated completion is 2024-06-30.

What interventions are being tested in trial NCT04039087?

The interventions under investigation include: Sildenafil 40mg oral capsule (DRUG), Placebo Oral capsule (DRUG).

Who is sponsoring clinical trial NCT04039087?

This trial is sponsored by National Jewish Health, which has 83 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.