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NCT04030572 · ClinicalTrials.gov registry record · Early Phase 1

Feasibility of Administering Clonidine as a Pharmacological Challenge in Imaging Studies

A Early Phase 1 study, sponsored by Weill Medical College of Cornell University.

Terminated
Registry status
Early Phase 1
Development phase
3
Enrollment target

NCT04030572: Clinical Trial Early Phase 1 study, sponsored by Weill Medical College of Cornell University.

NCT04030572 is a Early Phase 1 study that was terminated before completion, run by Weill Medical College of Cornell University. The registered enrollment target is 3 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04030572, a Early Phase 1 study, was terminated before completion, sponsored by Weill Medical College of Cornell University.

TERMINATED
Registry status
Early Phase 1
Development phase
3 participants
Enrollment target

Study Summary

This will be a Phase 1, open label study of the pharmacokinetics (PK) and pharmacodynamics (PD) of clonidine, an alpha-2 adrenergic (a2a) agonist, in healthy volunteers. The primary aim is to show that the drug regimen is safe and reasonably well tolerated. The secondary aim is to demonstrate that safety can be monitored with home health devices.

Primary Outcome

clinically significant drop in blood pressure or pulse

Interventions

  • DRUG Clonidine Pill

Trial Details

FieldValue
Enrollment Target 3 participants
Start Date 2019-12-10
Est. Completion 2020-03-17
Phase Early Phase 1

Why NCT04030572 stopped before completion

NCT04030572 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (94% lower).

The record links to 0 conditions, and to 1 intervention - of which Clonidine Pill is the first listed.

NCT04030572 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04030572 about?

NCT04030572 is a clinical study titled "Feasibility of Administering Clonidine as a Pharmacological Challenge in Imaging Studies". This will be a Phase 1, open label study of the pharmacokinetics (PK) and pharmacodynamics (PD) of clonidine, an alpha-2 adrenergic (a2a) agonist, in healthy volunteers. The primary aim is to show that the drug regimen is safe and reasonably well tolerated. The secondary aim is to demonstrate that s...

What is the current status of trial NCT04030572?

This trial is currently terminated. It is a Early Phase 1 study. The enrollment target is 3 participants. The study started on 2019-12-10. Estimated completion is 2020-03-17.

What interventions are being tested in trial NCT04030572?

The interventions under investigation include: Clonidine Pill (DRUG).

Who is sponsoring clinical trial NCT04030572?

This trial is sponsored by Weill Medical College of Cornell University, which has 701 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04030572's enrollment target sits among peer trials

3 1948th of 2000 higher than 28 of 2,000 other Early Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04030572, the US trial registry maintained by the National Library of Medicine. NCT04030572 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.