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NCT04020185 · ClinicalTrials.gov registry record · Phase 1
Safety and Efficacy Study of IMSA101 in Refractory Malignancies
A Phase 1 study, sponsored by ImmuneSensor Therapeutics.
- Completed
- Registry status
- Phase 1
- Development phase
- 40
- Enrollment target
NCT04020185: Completed Phase 1 study, sponsored by ImmuneSensor Therapeutics.
NCT04020185 is a Phase 1 study that has completed, run by ImmuneSensor Therapeutics. The registered enrollment target is 40 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04020185, a Phase 1 study, has completed, sponsored by ImmuneSensor Therapeutics.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 40 participants
- Enrollment target
Study Summary
Open-label, dose escalation (Phase I) and dose expansion (Phase IIA) study of patients receiving intra-tumoral IMSA101 alone or in combination with an immune checkpoint inhibitor (ICI) (Phase I and II)
Primary Outcome
Highest dose level of IMSA101 at which no more than 1 out of 6 patients experienced a dose limiting toxicity (DLT) during the first cycle (28 days) of therapy.
Interventions
- DRUG IMSA101
- DRUG Immune checkpoint inhibitor (ICI)
- DRUG Immuno-oncology (IO) therapy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2019-09-23 |
| Est. Completion | 2023-09-15 |
| Phase | Phase 1 |
What the finished NCT04020185 record still lists
NCT04020185 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% lower).
The record links to 0 conditions, and to 3 interventions - of which IMSA101 is the first listed.
NCT04020185 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04020185 about?
NCT04020185 is a clinical study titled "Safety and Efficacy Study of IMSA101 in Refractory Malignancies". Open-label, dose escalation (Phase I) and dose expansion (Phase IIA) study of patients receiving intra-tumoral IMSA101 alone or in combination with an immune checkpoint inhibitor (ICI) (Phase I and II)
What is the current status of trial NCT04020185?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2019-09-23. Estimated completion is 2023-09-15.
What interventions are being tested in trial NCT04020185?
The interventions under investigation include: IMSA101 (DRUG), Immune checkpoint inhibitor (ICI) (DRUG), Immuno-oncology (IO) therapy (DRUG).
Who is sponsoring clinical trial NCT04020185?
This trial is sponsored by ImmuneSensor Therapeutics, which has 4 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04020185's enrollment target sits among peer trials
40 1130th of 2000 higher than 810 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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