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NCT04019522 · ClinicalTrials.gov registry record · NA
American Heart Association- Stroke/Hypoxia Study
A NA study, sponsored by Shirley Ryan AbilityLab.
- Completed
- Registry status
- NA
- Development phase
- 16
- Enrollment target
NCT04019522: Completed NA study, sponsored by Shirley Ryan AbilityLab.
NCT04019522 is a NA study that has completed, run by Shirley Ryan AbilityLab. The registered enrollment target is 16 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04019522, a NA study, has completed, sponsored by Shirley Ryan AbilityLab.
- COMPLETED
- Registry status
- NA
- Development phase
- 16 participants
- Enrollment target
Study Summary
Of the 795,000 people who experience a stroke every year in the US, only a small percentage will achieve full recovery. While current therapies promote strength and endurance, none directly address the unique potential of the brain to reorganize following injury. The goal of this project is to explore the effects of a novel therapy, acute intermittent hypoxia (AIH). During this therapy, individuals receive brief bouts of reduced oxygen levels by inhalation through a face mask. (This is akin to being on top of a tall mountain). In brief exposures, AIH is known to trigger the release of specific proteins that help the brain adapt to oxygen reductions. Published results in people with incomplete spinal cord injury have shown that AIH enhances muscle strength and coordination rather quickly. The research team aims to study the effects of AIH in stroke survivors.
Primary Outcome
All adverse events will be reviewed for safety and study continuation by the medical monitor.
Interventions
- OTHER Acute Intermittent Hypoxia (AIH)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2019-07-15 |
| Est. Completion | 2025-07-01 |
| Phase | NA |
What the finished NCT04019522 record still lists
NCT04019522 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which Acute Intermittent Hypoxia (AIH) is the first listed.
NCT04019522 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04019522 about?
NCT04019522 is a clinical study titled "American Heart Association- Stroke/Hypoxia Study". Of the 795,000 people who experience a stroke every year in the US, only a small percentage will achieve full recovery. While current therapies promote strength and endurance, none directly address the unique potential of the brain to reorganize following injury. The goal of this project is to explo...
What is the current status of trial NCT04019522?
This trial is currently completed. It is a NA study. The enrollment target is 16 participants. The study started on 2019-07-15. Estimated completion is 2025-07-01.
What interventions are being tested in trial NCT04019522?
The interventions under investigation include: Acute Intermittent Hypoxia (AIH) (OTHER).
Who is sponsoring clinical trial NCT04019522?
This trial is sponsored by Shirley Ryan AbilityLab, which has 138 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04019522's enrollment target sits among peer trials
16 1871st of 2000 higher than 120 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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