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NCT04018612 · ClinicalTrials.gov registry record · Phase 2
A Study of Acetaminophen for Post Surgical Dental Pain
A Phase 2 study, sponsored by Nevakar.
- Completed
- Registry status
- Phase 2
- Development phase
- 110
- Enrollment target
NCT04018612: Completed Phase 2 study, sponsored by Nevakar.
NCT04018612 is a Phase 2 study that has completed, run by Nevakar. The registered enrollment target is 110 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (17% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04018612, a Phase 2 study, has completed, sponsored by Nevakar.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 110 participants
- Enrollment target
Study Summary
To assess the safety, tolerability, analgesic, efficacy and pharmacokinetics of high dose acetaminophen relative to placebo and low dose acetaminophen relative to placebo over a 24 hour period in patient experiencing moderate to severe pain following the surgical removal of third molar.
Primary Outcome
Pain Intensity was self-reported over 24 hours, using a pain rating of 0-10 on the Numerical Rating Scale (NRS), with score between 0-10 (0= no pain; 10 = worst imaginable pain). Time weighted sum of pain intensity difference from 0 to 24 hours was reported. Pain Intensity (PI-NPRS) was collected at initiation of Dose 1 (T0) and post dose 0.5, 0.75, 1, 1.25, 1.75, 2.25 3.25, 4.25, 5.25, 6.25, 7.25, 8.25, 9.25, 10.25, 11.25, 12.25 (± 5 min) and 14.25, 16.25, 18.25, 20.25, 22.25, and 24.25 (± 10 m
Interventions
- DRUG Acetaminophen
- OTHER Placebo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 110 participants |
| Start Date | 2019-04-25 |
| Est. Completion | 2019-08-15 |
| Phase | Phase 2 |
What the finished NCT04018612 record still lists
NCT04018612 is an interventional study that assigns participants to a tested intervention. The registered 110 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (17% lower).
The record links to 0 conditions, and to 2 interventions - of which Acetaminophen is the first listed.
NCT04018612 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04018612 about?
NCT04018612 is a clinical study titled "A Study of Acetaminophen for Post Surgical Dental Pain". To assess the safety, tolerability, analgesic, efficacy and pharmacokinetics of high dose acetaminophen relative to placebo and low dose acetaminophen relative to placebo over a 24 hour period in patient experiencing moderate to severe pain following the surgical removal of third molar.
What is the current status of trial NCT04018612?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 110 participants. The study started on 2019-04-25. Estimated completion is 2019-08-15.
What interventions are being tested in trial NCT04018612?
The interventions under investigation include: Acetaminophen (DRUG), Placebo (OTHER).
Who is sponsoring clinical trial NCT04018612?
This trial is sponsored by Nevakar, which has 4 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04018612's enrollment target sits among peer trials
110 632nd of 2000 higher than 1,361 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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