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NCT04009629 · ClinicalTrials.gov registry record · NA
Dementia Risk and Dynamic Response to Exercise
A NA study, sponsored by University of Kansas Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 61
- Enrollment target
NCT04009629: Completed NA study, sponsored by University of Kansas Medical Center.
NCT04009629 is a NA study that has completed, run by University of Kansas Medical Center. The registered enrollment target is 61 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04009629, a NA study, has completed, sponsored by University of Kansas Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 61 participants
- Enrollment target
Study Summary
Research suggests that physical exercise supports brain health and cognition as we age. The goal of this project is to examine the specific changes in brain blood flow and biological factors in the blood immediately after exercise in older adults who have the APOE4 gene, a genetic risk factor for developing Alzheimer's. Results from this study will help researchers and clinicians understand and measure changes in the body and brain as a function of exercise, and how those changes relate to Alzheimer's risk.
Primary Outcome
Cumulative cerebral blood flow measured by Arterial Spin Labeling MRI. The standard arterial spin labeling unit of measure is average milliliters per 100 grams of tissue per minute (mL/100g tissue/minute). For the present analysis, we summed perfusion over the entire acquisition period, 23.2 minutes, rather than averaging. Therefore the units are milliliters per 100 grams of tissue
Interventions
- BEHAVIORAL Moderate Intensity Aerobic Exercise
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 61 participants |
| Start Date | 2019-10-25 |
| Est. Completion | 2021-10-28 |
| Phase | NA |
What the finished NCT04009629 record still lists
NCT04009629 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 61 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 1 intervention - of which Moderate Intensity Aerobic Exercise is the first listed.
NCT04009629 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04009629 about?
NCT04009629 is a clinical study titled "Dementia Risk and Dynamic Response to Exercise". Research suggests that physical exercise supports brain health and cognition as we age. The goal of this project is to examine the specific changes in brain blood flow and biological factors in the blood immediately after exercise in older adults who have the APOE4 gene, a genetic risk factor for de...
What is the current status of trial NCT04009629?
This trial is currently completed. It is a NA study. The enrollment target is 61 participants. The study started on 2019-10-25. Estimated completion is 2021-10-28.
What interventions are being tested in trial NCT04009629?
The interventions under investigation include: Moderate Intensity Aerobic Exercise (BEHAVIORAL).
Who is sponsoring clinical trial NCT04009629?
This trial is sponsored by University of Kansas Medical Center, which has 408 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04009629's enrollment target sits among peer trials
61 1164th of 2000 higher than 837 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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