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NCT03997760 · ClinicalTrials.gov registry record · Phase 1

A Study of SHP655 (rADAMTS13) in Sickle Cell Disease

A Phase 1 study, sponsored by Shire.

Completed
Registry status
Phase 1
Development phase
19
Enrollment target

NCT03997760 is a Phase 1 study that has completed, run by Shire. The registered enrollment target is 19 participants.

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The verdict

NCT03997760, a Phase 1 study, has completed, sponsored by Shire.

COMPLETED
Registry status
Phase 1
Development phase
19 participants
Enrollment target

Study Summary

TAK-755 (previously known as SHP655) is a medicine used to treat sickle cell disease (SCD). The main aim of the study is to measure the safety and tolerability of TAK-755 in SCD participants. Study participants will receive TAK-755 or placebo on Day 1. Their SCD will be treated by their doctor according to their doctor's usual clinical practice. During the study, participants will be asked to follow-up on 13 days following SHP655 or placebo administration for safety assessment. Maximum duration of participation is expected to be about 2 months.

Interventions

  • OTHER Placebo
  • DRUG TAK-755

Trial Details

FieldValue
Enrollment Target 19 participants
Start Date 2019-10-21
Est. Completion 2022-10-26
Phase Phase 1

Sponsor

Shire

245 total trials

What the Registry Record Tells You About NCT03997760

The ClinicalTrials.gov registry entry for NCT03997760 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 19 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Shire, which has 245 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT03997760 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03997760 about?

NCT03997760 is a clinical study titled "A Study of SHP655 (rADAMTS13) in Sickle Cell Disease". TAK-755 (previously known as SHP655) is a medicine used to treat sickle cell disease (SCD). The main aim of the study is to measure the safety and tolerability of TAK-755 in SCD participants. Study participants will receive TAK-755 or placebo on Day 1. Their SCD will be treated by their doctor acco...

What is the current status of trial NCT03997760?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 19 participants. The study started on 2019-10-21. Estimated completion is 2022-10-26.

What interventions are being tested in trial NCT03997760?

The interventions under investigation include: Placebo (OTHER), TAK-755 (DRUG).

Who is sponsoring clinical trial NCT03997760?

This trial is sponsored by Shire, which has 245 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.