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NCT03987295 · ClinicalTrials.gov registry record · Phase 2
A Phase 2 Study to Evaluate Safety of Long-term AL001 Dosing in Frontotemporal Dementia (FTD) Patients (INFRONT-2)
A Phase 2 study, sponsored by Alector.
- Completed
- Registry status
- Phase 2
- Development phase
- 33
- Enrollment target
NCT03987295: Completed Phase 2 study, sponsored by Alector.
NCT03987295 is a Phase 2 study that has completed, run by Alector. The registered enrollment target is 33 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (75% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03987295, a Phase 2 study, has completed, sponsored by Alector.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 33 participants
- Enrollment target
Study Summary
A Phase 2 open label study evaluating the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of AL001 in participants with a Granulin mutation or C9orf72 mutation causative of frontotemporal dementia.
Primary Outcome
Number of TEAEs categorized by severity
Interventions
- DRUG AL001
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 33 participants |
| Start Date | 2019-09-27 |
| Est. Completion | 2024-06-05 |
| Phase | Phase 2 |
What the finished NCT03987295 record still lists
NCT03987295 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 33 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (75% lower).
The record links to 0 conditions, and to 1 intervention - of which AL001 is the first listed.
NCT03987295 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03987295 about?
NCT03987295 is a clinical study titled "A Phase 2 Study to Evaluate Safety of Long-term AL001 Dosing in Frontotemporal Dementia (FTD) Patients (INFRONT-2)". A Phase 2 open label study evaluating the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of AL001 in participants with a Granulin mutation or C9orf72 mutation causative of frontotemporal dementia.
What is the current status of trial NCT03987295?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 33 participants. The study started on 2019-09-27. Estimated completion is 2024-06-05.
What interventions are being tested in trial NCT03987295?
The interventions under investigation include: AL001 (DRUG).
Who is sponsoring clinical trial NCT03987295?
This trial is sponsored by Alector, which has 10 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03987295's enrollment target sits among peer trials
33 1553rd of 2000 higher than 438 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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