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NCT03974100 · ClinicalTrials.gov registry record · Phase 3

Study Investigating PK, PD, Efficacy, Safety, and Immunogenicity of Biosimilar Denosumab (GP2411) in Patients With Postmenopausal Osteoporosis

A Phase 3 study, sponsored by Sandoz.

Completed
Registry status
Phase 3
Development phase
527
Enrollment target

NCT03974100 is a Phase 3 study that has completed, run by Sandoz. The registered enrollment target is 527 participants.

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The verdict

NCT03974100, a Phase 3 study, has completed, sponsored by Sandoz.

COMPLETED
Registry status
Phase 3
Development phase
527 participants
Enrollment target

Study Summary

This study was conducted to assess if there were any clinically meaningful differences in pharmacokinetics (PK), pharmacodynamics (PD), efficacy, safety, or immunogenicity between GP2411 (proposed biosimilar denosumab) and EU-authorized Prolia® (denosumab).

Interventions

  • BIOLOGICAL GP2411
  • BIOLOGICAL EU-Prolia (EU-authorized Prolia®)

Trial Details

FieldValue
Enrollment Target 527 participants
Start Date 2019-07-02
Est. Completion 2022-04-22
Phase Phase 3

Sponsor

Sandoz

29 total trials

What the Registry Record Tells You About NCT03974100

The ClinicalTrials.gov registry entry for NCT03974100 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 527 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Sandoz, which has 29 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which GP2411 is the first listed.

NCT03974100 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03974100 about?

NCT03974100 is a clinical study titled "Study Investigating PK, PD, Efficacy, Safety, and Immunogenicity of Biosimilar Denosumab (GP2411) in Patients With Postmenopausal Osteoporosis". This study was conducted to assess if there were any clinically meaningful differences in pharmacokinetics (PK), pharmacodynamics (PD), efficacy, safety, or immunogenicity between GP2411 (proposed biosimilar denosumab) and EU-authorized Prolia® (denosumab).

What is the current status of trial NCT03974100?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 527 participants. The study started on 2019-07-02. Estimated completion is 2022-04-22.

What interventions are being tested in trial NCT03974100?

The interventions under investigation include: GP2411 (BIOLOGICAL), EU-Prolia (EU-authorized Prolia®) (BIOLOGICAL).

Who is sponsoring clinical trial NCT03974100?

This trial is sponsored by Sandoz, which has 29 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.